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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRX6 All Species: 17.58
Human Site: S39 Identified Species: 35.15
UniProt: P78412 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78412 NP_077311.2 446 48240 S39 R S V S D V A S G S T P A P A
Chimpanzee Pan troglodytes XP_001167355 444 48020 S39 R S V S D V A S G S T P A P A
Rhesus Macaque Macaca mulatta XP_001087101 444 48073 S39 R S V S D V A S G S T P A P T
Dog Lupus familis XP_544401 541 57810 A119 P R S V P D V A P G S T P A A
Cat Felis silvestris
Mouse Mus musculus Q9ER75 438 47224 S39 R S V S D V A S A S T S A S T
Rat Rattus norvegicus NP_001095883 443 47396 S39 R S V S D V A S A S T S A S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9YGS0 485 52755 P39 R T L P E S G P A A P A Q T P
Frog Xenopus laevis NP_001154863 495 55384 A39 R S L S D S A A A A S A Q T P
Zebra Danio Brachydanio rerio XP_691361 484 53120 S48 V T E G S S A S Q T A A S F C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24248 717 75403 T148 T D P V S G Q T V C S C Q Y D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93348 377 40765 V8 M I P I A N Q V K M E E P T T
Sea Urchin Strong. purpuratus NP_001123285 605 66354 H40 R P V A S D P H P G Q A V C C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 94.1 66.3 N.A. 75.7 76.2 N.A. N.A. 39.7 39.1 38.8 N.A. 26.3 N.A. 24.6 34
Protein Similarity: 100 98.4 95.7 69.8 N.A. 81.1 82.5 N.A. N.A. 51.7 52.7 53.3 N.A. 35.8 N.A. 39.2 46.6
P-Site Identity: 100 100 93.3 6.6 N.A. 73.3 73.3 N.A. N.A. 6.6 33.3 13.3 N.A. 0 N.A. 0 13.3
P-Site Similarity: 100 100 93.3 20 N.A. 73.3 73.3 N.A. N.A. 33.3 60 33.3 N.A. 13.3 N.A. 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 59 17 34 17 9 34 42 9 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 9 0 9 17 % C
% Asp: 0 9 0 0 50 17 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 0 9 0 9 0 0 0 0 0 9 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 9 0 9 9 0 25 17 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % K
% Leu: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 9 17 9 9 0 9 9 17 0 9 25 17 25 17 % P
% Gln: 0 0 0 0 0 0 17 0 9 0 9 0 25 0 0 % Q
% Arg: 67 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 50 9 50 25 25 0 50 0 42 25 17 9 17 0 % S
% Thr: 9 17 0 0 0 0 0 9 0 9 42 9 0 25 34 % T
% Val: 9 0 50 17 0 42 9 9 9 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _