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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRX6 All Species: 28.48
Human Site: T154 Identified Species: 56.97
UniProt: P78412 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78412 NP_077311.2 446 48240 T154 A G R R K N A T R E T T S T L
Chimpanzee Pan troglodytes XP_001167355 444 48020 T154 A G R R K N A T R E T T S T L
Rhesus Macaque Macaca mulatta XP_001087101 444 48073 T154 A G R R K N A T R E T T S T L
Dog Lupus familis XP_544401 541 57810 T234 T G R R K N A T R E T T S T L
Cat Felis silvestris
Mouse Mus musculus Q9ER75 438 47224 S154 R K N A T R E S T S A L K A W
Rat Rattus norvegicus NP_001095883 443 47396 S154 R K N A T R E S T S A L K A W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9YGS0 485 52755 S154 N A T R E T T S T L K A W L Q
Frog Xenopus laevis NP_001154863 495 55384 S154 N A T R E T T S T L K A W L Q
Zebra Danio Brachydanio rerio XP_691361 484 53120 T163 S T R R K N A T R E T T S T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24248 717 75403 T263 A A R R K N A T R E S T A T L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93348 377 40765 T123 G I K K R N A T R E A T A P L
Sea Urchin Strong. purpuratus NP_001123285 605 66354 S155 N A T R E T T S T L K A W L Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 94.1 66.3 N.A. 75.7 76.2 N.A. N.A. 39.7 39.1 38.8 N.A. 26.3 N.A. 24.6 34
Protein Similarity: 100 98.4 95.7 69.8 N.A. 81.1 82.5 N.A. N.A. 51.7 52.7 53.3 N.A. 35.8 N.A. 39.2 46.6
P-Site Identity: 100 100 100 93.3 N.A. 0 0 N.A. N.A. 6.6 6.6 86.6 N.A. 80 N.A. 46.6 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 6.6 6.6 N.A. N.A. 20 20 93.3 N.A. 93.3 N.A. 73.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 34 0 17 0 0 59 0 0 0 25 25 17 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 25 0 17 0 0 59 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 17 9 9 50 0 0 0 0 0 25 0 17 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 25 0 17 0 25 59 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 25 0 17 0 0 59 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % Q
% Arg: 17 0 50 75 9 17 0 0 59 0 0 0 0 0 0 % R
% Ser: 9 0 0 0 0 0 0 42 0 17 9 0 42 0 0 % S
% Thr: 9 9 25 0 17 25 25 59 42 0 42 59 0 50 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 17 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _