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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRX6
All Species:
16.36
Human Site:
T277
Identified Species:
32.73
UniProt:
P78412
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78412
NP_077311.2
446
48240
T277
E
D
E
E
V
V
A
T
A
G
D
R
L
T
E
Chimpanzee
Pan troglodytes
XP_001167355
444
48020
T276
E
D
E
E
V
V
A
T
A
G
D
R
L
T
E
Rhesus Macaque
Macaca mulatta
XP_001087101
444
48073
T276
E
D
K
E
V
V
A
T
A
A
D
R
L
T
E
Dog
Lupus familis
XP_544401
541
57810
A355
D
E
E
E
A
V
A
A
A
A
D
R
L
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER75
438
47224
S271
A
E
E
E
A
A
V
S
A
A
R
R
L
A
D
Rat
Rattus norvegicus
NP_001095883
443
47396
S276
E
K
E
E
A
A
V
S
A
A
R
R
L
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9YGS0
485
52755
A300
A
A
E
P
P
A
A
A
A
E
E
E
E
E
E
Frog
Xenopus laevis
NP_001154863
495
55384
K303
H
C
K
E
V
I
L
K
M
P
I
T
S
T
A
Zebra Danio
Brachydanio rerio
XP_691361
484
53120
S277
G
Q
D
D
L
P
T
S
S
P
P
K
R
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24248
717
75403
R383
L
G
Q
A
N
I
L
R
A
G
F
G
Y
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93348
377
40765
S232
H
L
A
S
P
T
P
S
G
G
S
G
G
S
D
Sea Urchin
Strong. purpuratus
NP_001123285
605
66354
N352
R
D
S
N
P
R
D
N
S
P
D
S
L
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
94.1
66.3
N.A.
75.7
76.2
N.A.
N.A.
39.7
39.1
38.8
N.A.
26.3
N.A.
24.6
34
Protein Similarity:
100
98.4
95.7
69.8
N.A.
81.1
82.5
N.A.
N.A.
51.7
52.7
53.3
N.A.
35.8
N.A.
39.2
46.6
P-Site Identity:
100
100
86.6
60
N.A.
33.3
40
N.A.
N.A.
26.6
20
0
N.A.
13.3
N.A.
6.6
20
P-Site Similarity:
100
100
93.3
73.3
N.A.
53.3
46.6
N.A.
N.A.
33.3
33.3
40
N.A.
26.6
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
9
9
25
25
42
17
67
34
0
0
0
17
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
34
9
9
0
0
9
0
0
0
42
0
0
9
17
% D
% Glu:
34
17
50
59
0
0
0
0
0
9
9
9
9
9
42
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
9
34
0
17
9
0
9
% G
% His:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
17
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
9
17
0
0
0
0
9
0
0
0
9
0
0
0
% K
% Leu:
9
9
0
0
9
0
17
0
0
0
0
0
59
0
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
9
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
25
9
9
0
0
25
9
0
0
9
0
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
9
0
0
0
0
9
0
9
0
0
17
50
9
0
0
% R
% Ser:
0
0
9
9
0
0
0
34
17
0
9
9
9
9
9
% S
% Thr:
0
0
0
0
0
9
9
25
0
0
0
9
0
34
0
% T
% Val:
0
0
0
0
34
34
17
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _