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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRX6 All Species: 26.36
Human Site: Y173 Identified Species: 52.73
UniProt: P78412 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78412 NP_077311.2 446 48240 Y173 N E H R K N P Y P T K G E K I
Chimpanzee Pan troglodytes XP_001167355 444 48020 Y173 N E H R K N P Y P T K G E K I
Rhesus Macaque Macaca mulatta XP_001087101 444 48073 Y173 N E H R K N P Y P T K G E K I
Dog Lupus familis XP_544401 541 57810 Y253 N E H R K N P Y P T K G E K I
Cat Felis silvestris
Mouse Mus musculus Q9ER75 438 47224 K173 R K N P Y P T K G E K I M L A
Rat Rattus norvegicus NP_001095883 443 47396 K173 R K N P Y P T K G E K I M L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9YGS0 485 52755 E173 N P Y P T K G E K I M L A I I
Frog Xenopus laevis NP_001154863 495 55384 E173 N P Y P T K G E K I M L A I I
Zebra Danio Brachydanio rerio XP_691361 484 53120 Y182 Y E H R K N P Y P T K G E K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24248 717 75403 Y282 N E H K K N P Y P T K G E K I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93348 377 40765 Y142 H S H R K N P Y P S K A D K V
Sea Urchin Strong. purpuratus NP_001123285 605 66354 E174 N P Y P T K G E K I M L A I I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 94.1 66.3 N.A. 75.7 76.2 N.A. N.A. 39.7 39.1 38.8 N.A. 26.3 N.A. 24.6 34
Protein Similarity: 100 98.4 95.7 69.8 N.A. 81.1 82.5 N.A. N.A. 51.7 52.7 53.3 N.A. 35.8 N.A. 39.2 46.6
P-Site Identity: 100 100 100 100 N.A. 6.6 6.6 N.A. N.A. 13.3 13.3 93.3 N.A. 93.3 N.A. 60 13.3
P-Site Similarity: 100 100 100 100 N.A. 20 20 N.A. N.A. 20 20 93.3 N.A. 100 N.A. 86.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 9 25 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % D
% Glu: 0 50 0 0 0 0 0 25 0 17 0 0 50 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 25 0 17 0 0 50 0 0 0 % G
% His: 9 0 59 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 25 0 17 0 25 75 % I
% Lys: 0 17 0 9 59 25 0 17 25 0 75 0 0 59 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 25 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 25 0 17 0 0 % M
% Asn: 67 0 17 0 0 59 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 25 0 42 0 17 59 0 59 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 17 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % S
% Thr: 0 0 0 0 25 0 17 0 0 50 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 25 0 17 0 0 59 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _