KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRX4
All Species:
9.7
Human Site:
S301
Identified Species:
19.39
UniProt:
P78413
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78413
NP_057442.1
519
54445
S301
D
G
P
V
K
E
A
S
G
A
L
R
M
S
L
Chimpanzee
Pan troglodytes
XP_001175262
293
32797
G125
Y
P
Y
E
P
A
L
G
Q
Y
P
Y
D
R
Y
Rhesus Macaque
Macaca mulatta
XP_001097842
515
54260
S299
D
D
R
V
K
E
A
S
G
A
L
R
M
P
L
Dog
Lupus familis
XP_535801
433
45370
R265
T
W
F
A
N
A
R
R
R
L
K
K
E
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY61
515
54682
S304
P
G
T
G
K
E
A
S
T
T
L
R
M
P
L
Rat
Rattus norvegicus
NP_001100800
515
54900
P304
P
G
T
G
K
E
A
P
V
T
L
R
M
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9YGS0
485
52755
G286
P
H
P
H
P
L
P
G
G
G
P
P
P
R
A
Frog
Xenopus laevis
NP_001090204
496
55506
C300
R
D
C
V
N
D
H
C
K
D
V
I
L
K
M
Zebra Danio
Brachydanio rerio
NP_991261
440
48812
A272
K
H
R
F
Q
I
S
A
H
M
E
T
K
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24248
717
75403
T463
C
G
V
P
I
P
A
T
K
P
K
I
W
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93348
377
40765
S206
D
D
D
M
N
R
P
S
S
S
T
S
I
N
S
Sea Urchin
Strong. purpuratus
NP_001123285
605
66354
H309
S
G
P
K
D
S
E
H
G
A
L
R
D
D
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.7
95.3
35.8
N.A.
82.8
81.5
N.A.
N.A.
67.4
59.3
56.8
N.A.
27.3
N.A.
24.6
34.3
Protein Similarity:
100
41
96.1
44.3
N.A.
87.6
85.5
N.A.
N.A.
75.1
70.7
67.4
N.A.
38.9
N.A.
37.5
46.6
P-Site Identity:
100
0
80
0
N.A.
60
53.3
N.A.
N.A.
13.3
6.6
0
N.A.
26.6
N.A.
13.3
40
P-Site Similarity:
100
0
80
13.3
N.A.
60
53.3
N.A.
N.A.
13.3
33.3
20
N.A.
33.3
N.A.
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
17
42
9
0
25
0
0
0
0
9
% A
% Cys:
9
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
25
25
9
0
9
9
0
0
0
9
0
0
17
17
0
% D
% Glu:
0
0
0
9
0
34
9
0
0
0
9
0
9
0
0
% E
% Phe:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
42
0
17
0
0
0
17
34
9
0
0
0
0
0
% G
% His:
0
17
0
9
0
0
9
9
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
0
0
0
17
9
0
0
% I
% Lys:
9
0
0
9
34
0
0
0
17
0
17
9
9
9
9
% K
% Leu:
0
0
0
0
0
9
9
0
0
9
42
0
9
0
42
% L
% Met:
0
0
0
9
0
0
0
0
0
9
0
0
34
0
9
% M
% Asn:
0
0
0
0
25
0
0
0
0
0
0
0
0
17
0
% N
% Pro:
25
9
25
9
17
9
17
9
0
9
17
9
9
25
9
% P
% Gln:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
9
0
17
0
0
9
9
9
9
0
0
42
0
17
0
% R
% Ser:
9
0
0
0
0
9
9
34
9
9
0
9
0
17
9
% S
% Thr:
9
0
17
0
0
0
0
9
9
17
9
9
0
0
0
% T
% Val:
0
0
9
25
0
0
0
0
9
0
9
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
9
0
9
0
0
0
0
0
0
9
0
9
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _