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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRX4
All Species:
8.18
Human Site:
S421
Identified Species:
16.36
UniProt:
P78413
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78413
NP_057442.1
519
54445
S421
P
S
V
A
L
P
H
S
G
A
L
D
R
H
Q
Chimpanzee
Pan troglodytes
XP_001175262
293
32797
E227
E
E
E
E
G
G
E
E
E
A
R
E
E
P
L
Rhesus Macaque
Macaca mulatta
XP_001097842
515
54260
S417
P
S
V
A
P
A
R
S
G
A
L
D
R
H
Q
Dog
Lupus familis
XP_535801
433
45370
L367
P
I
L
R
H
S
T
L
N
Q
A
W
A
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY61
515
54682
S417
S
P
A
V
T
A
P
S
G
A
L
D
R
H
Q
Rat
Rattus norvegicus
NP_001100800
515
54900
S417
S
P
A
V
P
A
A
S
G
T
L
D
R
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9YGS0
485
52755
V389
A
A
A
V
S
A
P
V
S
V
M
D
R
H
Q
Frog
Xenopus laevis
NP_001090204
496
55506
R407
T
P
V
C
V
I
D
R
R
Q
D
S
P
V
T
Zebra Danio
Brachydanio rerio
NP_991261
440
48812
N374
S
P
V
T
T
L
R
N
W
V
D
G
V
F
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24248
717
75403
D625
G
F
L
E
A
Q
P
D
T
P
P
Q
T
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93348
377
40765
M308
M
K
K
Q
M
E
V
M
A
R
L
D
P
T
L
Sea Urchin
Strong. purpuratus
NP_001123285
605
66354
H456
H
W
V
N
G
Q
F
H
G
I
P
L
P
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.7
95.3
35.8
N.A.
82.8
81.5
N.A.
N.A.
67.4
59.3
56.8
N.A.
27.3
N.A.
24.6
34.3
Protein Similarity:
100
41
96.1
44.3
N.A.
87.6
85.5
N.A.
N.A.
75.1
70.7
67.4
N.A.
38.9
N.A.
37.5
46.6
P-Site Identity:
100
6.6
80
6.6
N.A.
53.3
46.6
N.A.
N.A.
26.6
6.6
6.6
N.A.
0
N.A.
13.3
13.3
P-Site Similarity:
100
13.3
80
13.3
N.A.
53.3
46.6
N.A.
N.A.
40
13.3
13.3
N.A.
6.6
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
25
17
9
34
9
0
9
34
9
0
9
0
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
0
17
50
0
0
0
% D
% Glu:
9
9
9
17
0
9
9
9
9
0
0
9
9
0
0
% E
% Phe:
0
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% F
% Gly:
9
0
0
0
17
9
0
0
42
0
0
9
0
0
9
% G
% His:
9
0
0
0
9
0
9
9
0
0
0
0
0
42
9
% H
% Ile:
0
9
0
0
0
9
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
17
0
9
9
0
9
0
0
42
9
0
0
17
% L
% Met:
9
0
0
0
9
0
0
9
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
9
9
0
0
0
0
0
0
% N
% Pro:
25
34
0
0
17
9
25
0
0
9
17
0
25
25
9
% P
% Gln:
0
0
0
9
0
17
0
0
0
17
0
9
0
0
42
% Q
% Arg:
0
0
0
9
0
0
17
9
9
9
9
0
42
0
0
% R
% Ser:
25
17
0
0
9
9
0
34
9
0
0
9
0
0
0
% S
% Thr:
9
0
0
9
17
0
9
0
9
9
0
0
9
17
9
% T
% Val:
0
0
42
25
9
0
9
9
0
17
0
0
9
9
0
% V
% Trp:
0
9
0
0
0
0
0
0
9
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _