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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRX4 All Species: 15.45
Human Site: S434 Identified Species: 30.91
UniProt: P78413 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78413 NP_057442.1 519 54445 S434 H Q D S P V T S L R N W V D G
Chimpanzee Pan troglodytes XP_001175262 293 32797 A240 P L K S S K N A G R P S C R R
Rhesus Macaque Macaca mulatta XP_001097842 515 54260 S430 H Q D S P V T S L R N W V D G
Dog Lupus familis XP_535801 433 45370 D380 T A K G A L L D P G P L G R S
Cat Felis silvestris
Mouse Mus musculus Q9QY61 515 54682 S430 H Q D S P V T S L R N W V D G
Rat Rattus norvegicus NP_001100800 515 54900 S430 H Q D S P V T S L R N W V D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9YGS0 485 52755 N402 H Q D S P V T N L R N W V D G
Frog Xenopus laevis NP_001090204 496 55506 V420 V T S L R N W V D G V F H D P
Zebra Danio Brachydanio rerio NP_991261 440 48812 H387 F H D P L F R H S S L N Q T N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24248 717 75403 S638 P P N M K V L S G A L S L L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93348 377 40765 H321 T L F R H T M H P F M F Q L L
Sea Urchin Strong. purpuratus NP_001123285 605 66354 S469 P G F P L H H S Q L A L A A G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.7 95.3 35.8 N.A. 82.8 81.5 N.A. N.A. 67.4 59.3 56.8 N.A. 27.3 N.A. 24.6 34.3
Protein Similarity: 100 41 96.1 44.3 N.A. 87.6 85.5 N.A. N.A. 75.1 70.7 67.4 N.A. 38.9 N.A. 37.5 46.6
P-Site Identity: 100 13.3 100 0 N.A. 100 100 N.A. N.A. 93.3 6.6 6.6 N.A. 13.3 N.A. 0 13.3
P-Site Similarity: 100 20 100 6.6 N.A. 100 100 N.A. N.A. 100 13.3 6.6 N.A. 26.6 N.A. 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 0 0 9 0 9 9 0 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 50 0 0 0 0 9 9 0 0 0 0 50 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 17 0 0 9 0 0 0 9 0 17 0 0 0 % F
% Gly: 0 9 0 9 0 0 0 0 17 17 0 0 9 0 50 % G
% His: 42 9 0 0 9 9 9 17 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 17 0 9 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 17 0 9 17 9 17 0 42 9 17 17 9 17 9 % L
% Met: 0 0 0 9 0 0 9 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 9 0 0 9 9 9 0 0 42 9 0 0 9 % N
% Pro: 25 9 0 17 42 0 0 0 17 0 17 0 0 0 17 % P
% Gln: 0 42 0 0 0 0 0 0 9 0 0 0 17 0 0 % Q
% Arg: 0 0 0 9 9 0 9 0 0 50 0 0 0 17 9 % R
% Ser: 0 0 9 50 9 0 0 50 9 9 0 17 0 0 9 % S
% Thr: 17 9 0 0 0 9 42 0 0 0 0 0 0 9 0 % T
% Val: 9 0 0 0 0 50 0 9 0 0 9 0 42 0 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 42 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _