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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRX4
All Species:
1.21
Human Site:
T144
Identified Species:
2.42
UniProt:
P78413
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78413
NP_057442.1
519
54445
T144
Y
G
T
M
D
S
G
T
R
R
K
N
A
T
R
Chimpanzee
Pan troglodytes
XP_001175262
293
32797
Rhesus Macaque
Macaca mulatta
XP_001097842
515
54260
R144
T
M
D
S
G
T
R
R
K
N
A
T
R
E
T
Dog
Lupus familis
XP_535801
433
45370
L128
C
P
V
Y
E
S
R
L
L
A
T
A
R
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY61
515
54682
G144
R
Y
G
T
V
D
S
G
T
R
R
K
N
A
T
Rat
Rattus norvegicus
NP_001100800
515
54900
G144
R
Y
G
T
V
D
S
G
T
R
R
K
N
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9YGS0
485
52755
R144
G
A
M
D
G
G
T
R
R
K
N
A
T
R
E
Frog
Xenopus laevis
NP_001090204
496
55506
R144
G
T
M
D
G
S
S
R
R
K
N
A
T
R
E
Zebra Danio
Brachydanio rerio
NP_991261
440
48812
S134
Y
Q
Y
D
R
Y
G
S
M
E
G
G
T
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24248
717
75403
A257
G
A
S
Y
D
L
A
A
R
R
K
N
A
T
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93348
377
40765
A69
A
A
Q
Q
A
T
L
A
G
F
P
G
V
P
M
Sea Urchin
Strong. purpuratus
NP_001123285
605
66354
A144
Y
G
M
D
L
N
G
A
R
R
K
N
A
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.7
95.3
35.8
N.A.
82.8
81.5
N.A.
N.A.
67.4
59.3
56.8
N.A.
27.3
N.A.
24.6
34.3
Protein Similarity:
100
41
96.1
44.3
N.A.
87.6
85.5
N.A.
N.A.
75.1
70.7
67.4
N.A.
38.9
N.A.
37.5
46.6
P-Site Identity:
100
0
0
6.6
N.A.
6.6
6.6
N.A.
N.A.
6.6
13.3
20
N.A.
53.3
N.A.
0
66.6
P-Site Similarity:
100
0
13.3
13.3
N.A.
13.3
13.3
N.A.
N.A.
13.3
20
26.6
N.A.
60
N.A.
6.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
0
0
9
0
9
25
0
9
9
25
25
17
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
34
17
17
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
9
0
0
0
9
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
25
17
17
0
25
9
25
17
9
0
9
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
17
25
17
0
0
0
% K
% Leu:
0
0
0
0
9
9
9
9
9
0
0
0
0
0
0
% L
% Met:
0
9
25
9
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
9
0
0
0
9
17
25
17
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
9
0
0
9
0
% P
% Gln:
0
9
9
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
17
0
0
0
9
0
17
25
42
42
17
0
17
25
34
% R
% Ser:
0
0
9
9
0
25
25
9
0
0
0
0
0
0
0
% S
% Thr:
9
9
9
17
0
17
9
9
17
0
9
9
25
25
25
% T
% Val:
0
0
9
0
17
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
17
9
17
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _