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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRX1
All Species:
14.55
Human Site:
S241
Identified Species:
32
UniProt:
P78414
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78414
NP_077313.3
480
49621
S241
D
E
H
D
G
D
Q
S
N
E
D
D
E
D
K
Chimpanzee
Pan troglodytes
XP_001175374
502
51398
S263
D
E
H
D
G
D
Q
S
N
E
D
D
E
D
K
Rhesus Macaque
Macaca mulatta
Q8MID6
249
27534
N43
D
T
S
I
M
L
R
N
N
A
D
T
G
K
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P81068
480
50136
S241
D
E
R
D
G
D
Q
S
N
E
D
E
E
D
K
Rat
Rattus norvegicus
NP_001100801
480
50115
S241
D
E
R
D
G
D
Q
S
N
E
D
E
E
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511678
479
51994
A232
N
E
E
E
E
D
K
A
E
A
L
R
P
S
Q
Chicken
Gallus gallus
Q9YGS0
485
52755
S268
D
A
A
E
S
E
S
S
E
C
E
M
R
R
P
Frog
Xenopus laevis
NP_001154863
495
55384
L255
R
E
E
K
A
L
D
L
S
D
L
E
D
F
D
Zebra Danio
Brachydanio rerio
NP_997067
426
46690
D220
I
D
I
D
K
I
D
D
N
D
G
D
Q
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54269
693
73649
K351
V
D
S
S
G
D
Q
K
L
D
L
D
R
E
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93348
377
40765
R170
S
T
W
F
A
N
A
R
R
R
L
K
K
E
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
20.2
N.A.
N.A.
91.2
90.4
N.A.
62
28.8
29
61.2
N.A.
29
N.A.
27.9
N.A.
Protein Similarity:
100
94.6
29.3
N.A.
N.A.
93.3
92.9
N.A.
68.3
42.6
43.2
68.7
N.A.
40.1
N.A.
40.8
N.A.
P-Site Identity:
100
100
20
N.A.
N.A.
86.6
86.6
N.A.
13.3
13.3
6.6
20
N.A.
26.6
N.A.
0
N.A.
P-Site Similarity:
100
100
33.3
N.A.
N.A.
93.3
93.3
N.A.
46.6
33.3
33.3
40
N.A.
46.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
19
0
10
10
0
19
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
55
19
0
46
0
55
19
10
0
28
46
37
10
37
10
% D
% Glu:
0
55
19
19
10
10
0
0
19
37
10
28
37
19
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
46
0
0
0
0
0
10
0
10
0
0
% G
% His:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
10
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
10
10
0
0
0
10
10
10
37
% K
% Leu:
0
0
0
0
0
19
0
10
10
0
37
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
0
0
10
0
10
55
0
0
0
0
0
19
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
19
% P
% Gln:
0
0
0
0
0
0
46
0
0
0
0
0
10
0
10
% Q
% Arg:
10
0
19
0
0
0
10
10
10
10
0
10
19
10
0
% R
% Ser:
10
0
19
10
10
0
10
46
10
0
0
0
0
19
0
% S
% Thr:
0
19
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _