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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRX1 All Species: 14.85
Human Site: Y76 Identified Species: 32.67
UniProt: P78414 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78414 NP_077313.3 480 49621 Y76 P Y A G A P N Y S A F L P Y A
Chimpanzee Pan troglodytes XP_001175374 502 51398 Y98 P Y A G A P N Y S A F L P Y A
Rhesus Macaque Macaca mulatta Q8MID6 249 27534
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P81068 480 50136 Y76 P Y A G G P N Y S A F L P Y A
Rat Rattus norvegicus NP_001100801 480 50115 Y76 P Y A G A P N Y S A F L P Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511678 479 51994 S70 P R S S V T V S F G V W A K G
Chicken Gallus gallus Q9YGS0 485 52755 G90 Y G N Y V T Y G T E A P A F Y
Frog Xenopus laevis NP_001154863 495 55384 G90 Y G N Y V T Y G A D A P S F Y
Zebra Danio Brachydanio rerio NP_997067 426 46690 Y58 S V L G M Y P Y A H N Y S A F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54269 693 73649 F175 I G V D N S A F Y A P L S N P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93348 377 40765 V8 M I P I A N Q V K M E E P T T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.2 20.2 N.A. N.A. 91.2 90.4 N.A. 62 28.8 29 61.2 N.A. 29 N.A. 27.9 N.A.
Protein Similarity: 100 94.6 29.3 N.A. N.A. 93.3 92.9 N.A. 68.3 42.6 43.2 68.7 N.A. 40.1 N.A. 40.8 N.A.
P-Site Identity: 100 100 0 N.A. N.A. 93.3 100 N.A. 6.6 0 0 13.3 N.A. 13.3 N.A. 13.3 N.A.
P-Site Similarity: 100 100 0 N.A. N.A. 93.3 100 N.A. 13.3 13.3 13.3 20 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 37 0 37 0 10 0 19 46 19 0 19 10 37 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 10 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 10 0 37 0 0 19 10 % F
% Gly: 0 28 0 46 10 0 0 19 0 10 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 10 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % K
% Leu: 0 0 10 0 0 0 0 0 0 0 0 46 0 0 0 % L
% Met: 10 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 19 0 10 10 37 0 0 0 10 0 0 10 0 % N
% Pro: 46 0 10 0 0 37 10 0 0 0 10 19 46 0 10 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 10 10 0 10 0 10 37 0 0 0 28 0 0 % S
% Thr: 0 0 0 0 0 28 0 0 10 0 0 0 0 10 10 % T
% Val: 0 10 10 0 28 0 10 10 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 19 37 0 19 0 10 19 46 10 0 0 10 0 37 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _