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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRX3 All Species: 6.97
Human Site: S321 Identified Species: 13.94
UniProt: P78415 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78415 NP_077312.2 501 52119 S321 P P P V A V A S P S L P S P P
Chimpanzee Pan troglodytes XP_510969 500 52128 S321 P P P V A V A S P S L P S P P
Rhesus Macaque Macaca mulatta XP_001092738 409 42853 L252 L P I P T S A L Q K P K I W S
Dog Lupus familis XP_544403 503 52123 P322 P P P V A A V P P S P P S P P
Cat Felis silvestris
Mouse Mus musculus P81067 507 52675 P324 P P P V A R A P A S P P S P P
Rat Rattus norvegicus NP_001100801 480 50115 K313 L Q G A P H S K P K I W S L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511678 479 51994 S307 P D G I L K S S P P P P P P P
Chicken Gallus gallus Q9YGS0 485 52755 A326 A A E E C E A A L L G A R P R
Frog Xenopus laevis NP_001154863 495 55384 L325 K I C H K T G L D Q C E Q D L
Zebra Danio Brachydanio rerio NP_571342 420 46871 H264 V K D G K E I H G D R A E H F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54269 693 73649 L481 P P P T A A Y L G Q N F Y P P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93348 377 40765 F221 E R K G E S L F G K P H L A S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.4 80.4 94.6 N.A. 91.1 41.1 N.A. 34.1 33.5 30.1 47.3 N.A. 25.6 N.A. 27.7 N.A.
Protein Similarity: 100 97.4 80.6 95.4 N.A. 92.6 54 N.A. 47.1 45.3 43.1 57.6 N.A. 36.6 N.A. 40.9 N.A.
P-Site Identity: 100 100 13.3 73.3 N.A. 73.3 13.3 N.A. 40 13.3 0 0 N.A. 40 N.A. 0 N.A.
P-Site Similarity: 100 100 13.3 73.3 N.A. 73.3 26.6 N.A. 53.3 20 0 0 N.A. 40 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 9 42 17 42 9 9 0 0 17 0 9 9 % A
% Cys: 0 0 9 0 9 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 9 9 0 0 0 0 0 9 9 0 0 0 9 0 % D
% Glu: 9 0 9 9 9 17 0 0 0 0 0 9 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 9 % F
% Gly: 0 0 17 17 0 0 9 0 25 0 9 0 0 0 0 % G
% His: 0 0 0 9 0 9 0 9 0 0 0 9 0 9 0 % H
% Ile: 0 9 9 9 0 0 9 0 0 0 9 0 9 0 0 % I
% Lys: 9 9 9 0 17 9 0 9 0 25 0 9 0 0 0 % K
% Leu: 17 0 0 0 9 0 9 25 9 9 17 0 9 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 50 50 42 9 9 0 0 17 42 9 42 42 9 59 50 % P
% Gln: 0 9 0 0 0 0 0 0 9 17 0 0 9 0 0 % Q
% Arg: 0 9 0 0 0 9 0 0 0 0 9 0 9 0 9 % R
% Ser: 0 0 0 0 0 17 17 25 0 34 0 0 42 0 17 % S
% Thr: 0 0 0 9 9 9 0 0 0 0 0 0 0 0 0 % T
% Val: 9 0 0 34 0 17 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _