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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU6F2 All Species: 4.55
Human Site: S427 Identified Species: 11.11
UniProt: P78424 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78424 NP_009183.3 683 72409 S427 N L L H L A H S Q A S M S Q S
Chimpanzee Pan troglodytes XP_527726 668 71862 S412 N L L H L A H S Q A S M S Q S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540368 622 65629 V393 S S S S A L S V G Q L V S N P
Cat Felis silvestris
Mouse Mus musculus Q8BJI4 691 73291 G435 N L L H L A H G Q A A T S H S
Rat Rattus norvegicus P56223 301 32683 P73 Q P V A V R K P S T P E S P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512107 672 71126 A418 L H L A H S Q A S M S Q S P V
Chicken Gallus gallus Q9YGL7 363 40431 Q135 V N G V S T L Q S S L T P C L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio P31367 610 63106 K382 S T A S V L P K A T V P L T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391982 671 72301 L439 R P E Q S S P L N E S V V S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785865 586 60667 G358 S S Q A S Q V G G V T Q V P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.9 N.A. 83 N.A. 92.4 31.6 N.A. 88.1 22.1 N.A. 35.2 N.A. N.A. 25.6 N.A. 35.8
Protein Similarity: 100 82.1 N.A. 85.6 N.A. 93.1 37.3 N.A. 90.1 32.2 N.A. 49.3 N.A. N.A. 40.2 N.A. 46.7
P-Site Identity: 100 100 N.A. 6.6 N.A. 73.3 6.6 N.A. 20 0 N.A. 0 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 N.A. 20 N.A. 80 26.6 N.A. 33.3 6.6 N.A. 13.3 N.A. N.A. 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 30 10 30 0 10 10 30 10 0 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 10 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 20 20 0 0 0 0 0 10 % G
% His: 0 10 0 30 10 0 30 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % K
% Leu: 10 30 40 0 30 20 10 10 0 0 20 0 10 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 20 0 0 0 % M
% Asn: 30 10 0 0 0 0 0 0 10 0 0 0 0 10 0 % N
% Pro: 0 20 0 0 0 0 20 10 0 0 10 10 10 30 10 % P
% Gln: 10 0 10 10 0 10 10 10 30 10 0 20 0 20 0 % Q
% Arg: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 30 20 10 20 30 20 10 20 30 10 40 0 60 10 30 % S
% Thr: 0 10 0 0 0 10 0 0 0 20 10 20 0 10 0 % T
% Val: 10 0 10 10 20 0 10 10 0 10 10 20 20 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _