KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX6-1
All Species:
4.55
Human Site:
Y326
Identified Species:
9.09
UniProt:
P78426
Number Species:
11
Phosphosite Substitution
Charge Score:
0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78426
NP_006159
367
37849
Y326
N
E
E
E
D
D
D
Y
N
K
P
L
D
P
N
Chimpanzee
Pan troglodytes
XP_521638
440
46674
K358
G
R
G
P
A
R
G
K
E
P
Q
R
Q
P
P
Rhesus Macaque
Macaca mulatta
XP_001104458
366
37790
Y326
N
D
E
E
D
D
D
Y
N
K
P
L
D
P
N
Dog
Lupus familis
XP_544960
366
37787
D326
E
N
E
E
E
D
D
D
Y
N
K
P
L
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99MA9
365
37687
D325
S
E
N
E
E
D
D
D
D
Y
N
K
P
L
D
Rat
Rattus norvegicus
O35762
365
37671
D325
S
E
N
E
E
D
D
D
D
Y
N
K
P
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510049
265
28997
E225
S
G
D
R
T
A
S
E
N
E
D
D
E
Y
N
Chicken
Gallus gallus
O93367
297
32351
Q255
Q
L
Q
H
D
A
F
Q
K
S
L
N
E
S
I
Frog
Xenopus laevis
A5YC49
254
27880
D214
P
G
D
L
I
P
S
D
N
E
D
D
E
Y
S
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
E255
R
V
P
I
L
Y
H
E
N
S
A
S
E
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
L107
R
S
E
L
A
K
R
L
D
V
T
E
T
Q
V
Sea Urchin
Strong. purpuratus
Q26656
405
44721
A343
V
S
A
V
H
V
H
A
Y
A
Q
R
M
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.5
99.1
97.8
N.A.
96.4
96.4
N.A.
39.5
25.8
34.5
22.3
N.A.
N.A.
N.A.
22.3
22.7
Protein Similarity:
100
34.5
99.4
97.8
N.A.
97.2
97
N.A.
48.7
35.1
44.4
36.5
N.A.
N.A.
N.A.
29.7
36
P-Site Identity:
100
6.6
93.3
26.6
N.A.
26.6
26.6
N.A.
13.3
6.6
6.6
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
6.6
100
33.3
N.A.
53.3
53.3
N.A.
40
20
33.3
13.3
N.A.
N.A.
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
17
17
0
9
0
9
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
17
0
25
42
42
34
25
0
17
17
17
9
17
% D
% Glu:
9
25
34
42
25
0
0
17
9
17
0
9
34
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
9
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
9
0
17
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
9
0
9
9
17
9
17
0
0
0
% K
% Leu:
0
9
0
17
9
0
0
9
0
0
9
17
9
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
17
9
17
0
0
0
0
0
42
9
17
9
0
0
25
% N
% Pro:
9
0
9
9
0
9
0
0
0
9
17
9
17
25
17
% P
% Gln:
9
0
9
0
0
0
0
9
0
0
17
0
9
9
0
% Q
% Arg:
17
9
0
9
0
9
9
0
0
0
0
17
0
0
9
% R
% Ser:
25
17
0
0
0
0
17
0
0
17
0
9
0
17
9
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
9
0
9
0
9
% T
% Val:
9
9
0
9
0
9
0
0
0
9
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
17
17
17
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _