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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
JAG1
All Species:
28.79
Human Site:
S1105
Identified Species:
52.78
UniProt:
P78504
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78504
NP_000205.1
1218
133799
S1105
K
P
G
S
H
T
H
S
A
S
E
D
N
T
T
Chimpanzee
Pan troglodytes
XP_001169666
1218
133732
S1105
K
P
G
S
H
T
H
S
A
S
E
D
N
T
T
Rhesus Macaque
Macaca mulatta
XP_001116216
1220
134468
S1107
K
P
G
S
H
T
H
S
A
S
E
D
N
T
T
Dog
Lupus familis
XP_542892
1218
133767
S1105
K
P
S
S
H
A
R
S
A
S
E
D
N
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXX0
1218
134146
S1105
K
P
S
S
H
T
H
S
A
P
E
D
N
T
T
Rat
Rattus norvegicus
Q63722
1219
134308
H1105
R
K
P
S
S
H
T
H
S
A
P
E
D
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514910
1426
156076
S1313
K
Q
S
S
H
T
R
S
A
S
E
D
N
T
T
Chicken
Gallus gallus
XP_415035
1311
143036
T1198
K
Q
S
S
H
T
H
T
A
S
D
D
N
T
T
Frog
Xenopus laevis
P21783
2524
275106
F1767
Q
L
W
F
P
D
G
F
I
P
K
E
P
S
K
Zebra Danio
Brachydanio rerio
Q90Y54
1213
133348
T1101
K
Q
N
T
H
S
N
T
A
T
S
A
T
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18168
1404
150325
L1256
R
T
S
S
G
M
N
L
T
P
S
L
D
A
L
Honey Bee
Apis mellifera
XP_394560
1331
142847
T1197
Q
R
S
S
L
T
A
T
T
S
S
E
T
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
G965
T
S
T
G
M
M
L
G
D
Y
M
T
Y
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.6
97.4
N.A.
96.5
96.3
N.A.
73.8
81.2
20.5
74.3
N.A.
30.7
38.6
N.A.
28.8
Protein Similarity:
100
99.6
98.1
98.7
N.A.
98
97.6
N.A.
79
86.5
31.8
84.6
N.A.
46.3
53.7
N.A.
41.7
P-Site Identity:
100
100
100
80
N.A.
86.6
13.3
N.A.
80
73.3
0
20
N.A.
6.6
20
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
86.6
46.6
N.A.
80
86.6
26.6
53.3
N.A.
26.6
46.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
62
8
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
0
8
54
16
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
47
24
0
8
8
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
24
8
8
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
62
8
39
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
62
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% K
% Leu:
0
8
0
0
8
0
8
8
0
0
0
8
0
0
16
% L
% Met:
0
0
0
0
8
16
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
16
0
0
0
0
0
54
16
0
% N
% Pro:
0
39
8
0
8
0
0
0
0
24
8
0
8
0
0
% P
% Gln:
16
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
8
0
0
0
0
16
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
47
77
8
8
0
47
8
54
24
0
0
16
0
% S
% Thr:
8
8
8
8
0
54
8
24
16
8
0
8
16
54
62
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _