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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: JAG1 All Species: 37.58
Human Site: S1210 Identified Species: 68.89
UniProt: P78504 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78504 NP_000205.1 1218 133799 S1210 R D L E S A Q S L N R M E Y I
Chimpanzee Pan troglodytes XP_001169666 1218 133732 S1210 R D L E S A Q S L N R M E Y I
Rhesus Macaque Macaca mulatta XP_001116216 1220 134468 S1212 R D L E S A Q S L N R M E Y I
Dog Lupus familis XP_542892 1218 133767 S1210 R D L E S A Q S L N R M E Y I
Cat Felis silvestris
Mouse Mus musculus Q9QXX0 1218 134146 S1210 R D L E S A Q S L N R M E Y I
Rat Rattus norvegicus Q63722 1219 134308 S1211 R D L E S A Q S L N R M E Y I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514910 1426 156076 S1418 R D L E S A Q S L N R M E Y I
Chicken Gallus gallus XP_415035 1311 143036 S1303 R D L E S A Q S L N R M E Y I
Frog Xenopus laevis P21783 2524 275106 A2259 A A G S N R M A F D A M V P R
Zebra Danio Brachydanio rerio Q90Y54 1213 133348 S1205 R D L E T A Q S L N R M E Y I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18168 1404 150325 P1388 I N C K S M P P S S G D E G S
Honey Bee Apis mellifera XP_394560 1331 142847 R1305 H K P Y S K P R L Q E P T Y S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P10079 1064 112055 S1057 K W T R Y E Q S I A P Q P D A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.6 97.4 N.A. 96.5 96.3 N.A. 73.8 81.2 20.5 74.3 N.A. 30.7 38.6 N.A. 28.8
Protein Similarity: 100 99.6 98.1 98.7 N.A. 98 97.6 N.A. 79 86.5 31.8 84.6 N.A. 46.3 53.7 N.A. 41.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 6.6 93.3 N.A. 13.3 20 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 26.6 100 N.A. 33.3 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 70 0 8 0 8 8 0 0 0 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 70 0 0 0 0 0 0 0 8 0 8 0 8 0 % D
% Glu: 0 0 0 70 0 8 0 0 0 0 8 0 77 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 8 0 0 8 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 70 % I
% Lys: 8 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 70 0 0 0 0 0 77 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 8 0 0 0 0 77 0 0 0 % M
% Asn: 0 8 0 0 8 0 0 0 0 70 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 16 8 0 0 8 8 8 8 0 % P
% Gln: 0 0 0 0 0 0 77 0 0 8 0 8 0 0 0 % Q
% Arg: 70 0 0 8 0 8 0 8 0 0 70 0 0 0 8 % R
% Ser: 0 0 0 8 77 0 0 77 8 8 0 0 0 0 16 % S
% Thr: 0 0 8 0 8 0 0 0 0 0 0 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 0 0 0 0 0 0 0 0 77 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _