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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
JAG1
All Species:
38.48
Human Site:
T219
Identified Species:
70.56
UniProt:
P78504
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78504
NP_000205.1
1218
133799
T219
C
D
Q
N
G
N
K
T
C
M
E
G
W
M
G
Chimpanzee
Pan troglodytes
XP_001169666
1218
133732
T219
C
D
Q
N
G
N
K
T
C
M
E
G
W
M
G
Rhesus Macaque
Macaca mulatta
XP_001116216
1220
134468
T219
C
D
Q
N
G
N
K
T
C
M
E
G
W
M
G
Dog
Lupus familis
XP_542892
1218
133767
T219
C
D
Q
N
G
N
K
T
C
M
E
G
W
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXX0
1218
134146
T219
C
D
Q
N
G
N
K
T
C
M
E
G
W
M
G
Rat
Rattus norvegicus
Q63722
1219
134308
T219
C
D
Q
N
G
N
K
T
C
M
E
G
W
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514910
1426
156076
T371
C
D
Q
N
G
N
K
T
C
M
E
G
W
M
G
Chicken
Gallus gallus
XP_415035
1311
143036
T311
C
D
Q
N
G
N
K
T
C
L
E
G
W
T
G
Frog
Xenopus laevis
P21783
2524
275106
T243
D
D
T
S
Y
D
C
T
C
L
P
G
F
S
G
Zebra Danio
Brachydanio rerio
Q90Y54
1213
133348
T216
C
D
Q
N
G
N
K
T
C
L
E
G
W
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18168
1404
150325
L269
C
G
S
E
G
Q
K
L
C
L
N
G
W
Q
G
Honey Bee
Apis mellifera
XP_394560
1331
142847
V329
C
D
E
N
G
D
K
V
C
I
Q
G
W
K
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
E134
N
Q
A
L
G
S
F
E
G
N
L
T
Q
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.6
97.4
N.A.
96.5
96.3
N.A.
73.8
81.2
20.5
74.3
N.A.
30.7
38.6
N.A.
28.8
Protein Similarity:
100
99.6
98.1
98.7
N.A.
98
97.6
N.A.
79
86.5
31.8
84.6
N.A.
46.3
53.7
N.A.
41.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
33.3
86.6
N.A.
46.6
60
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
60
93.3
N.A.
53.3
86.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
85
0
0
0
0
0
8
0
93
0
0
0
0
0
0
% C
% Asp:
8
85
0
0
0
16
0
0
0
0
0
0
0
8
8
% D
% Glu:
0
0
8
8
0
0
0
8
0
0
70
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
93
0
0
0
8
0
0
93
0
0
93
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
85
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
8
0
0
0
8
0
31
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
54
0
0
0
54
0
% M
% Asn:
8
0
0
77
0
70
0
0
0
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
8
70
0
0
8
0
0
0
0
8
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
0
8
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
77
0
0
0
8
0
16
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
85
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _