KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
JAG1
All Species:
35.15
Human Site:
Y1139
Identified Species:
64.44
UniProt:
P78504
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78504
NP_000205.1
1218
133799
Y1139
N
T
V
P
I
K
D
Y
E
N
K
N
S
K
M
Chimpanzee
Pan troglodytes
XP_001169666
1218
133732
Y1139
N
T
V
P
I
K
D
Y
E
N
K
N
S
K
M
Rhesus Macaque
Macaca mulatta
XP_001116216
1220
134468
Y1141
N
T
V
P
I
K
D
Y
E
N
K
N
S
K
M
Dog
Lupus familis
XP_542892
1218
133767
Y1139
N
T
V
P
V
K
D
Y
E
N
K
N
S
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXX0
1218
134146
Y1139
N
T
V
P
I
K
D
Y
E
N
K
N
S
K
M
Rat
Rattus norvegicus
Q63722
1219
134308
Y1140
N
T
V
P
I
K
D
Y
E
N
K
N
S
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514910
1426
156076
Y1347
N
A
V
P
I
K
D
Y
E
N
K
N
S
K
I
Chicken
Gallus gallus
XP_415035
1311
143036
Y1232
N
T
V
P
I
K
D
Y
E
N
K
N
S
K
I
Frog
Xenopus laevis
P21783
2524
275106
F1990
T
D
L
D
A
R
M
F
D
G
T
T
P
L
I
Zebra Danio
Brachydanio rerio
Q90Y54
1213
133348
Y1138
H
G
V
P
I
K
D
Y
E
G
K
N
S
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18168
1404
150325
A1314
P
E
L
A
A
S
A
A
S
S
S
A
L
H
R
Honey Bee
Apis mellifera
XP_394560
1331
142847
Q1234
Y
A
N
P
L
K
E
Q
D
Q
G
E
P
R
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
F993
Y
A
S
N
N
Y
D
F
P
S
F
G
F
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.6
97.4
N.A.
96.5
96.3
N.A.
73.8
81.2
20.5
74.3
N.A.
30.7
38.6
N.A.
28.8
Protein Similarity:
100
99.6
98.1
98.7
N.A.
98
97.6
N.A.
79
86.5
31.8
84.6
N.A.
46.3
53.7
N.A.
41.7
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
93.3
0
66.6
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
33.3
80
N.A.
13.3
46.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
8
16
0
8
8
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
77
0
16
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
8
0
70
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
8
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
16
8
8
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
62
0
0
0
0
0
0
0
0
8
31
% I
% Lys:
0
0
0
0
0
77
0
0
0
0
70
0
0
62
0
% K
% Leu:
0
0
16
0
8
0
0
0
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
47
% M
% Asn:
62
0
8
8
8
0
0
0
0
62
0
70
0
0
0
% N
% Pro:
8
0
0
77
0
0
0
0
8
0
0
0
16
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% R
% Ser:
0
0
8
0
0
8
0
0
8
16
8
0
70
0
0
% S
% Thr:
8
54
0
0
0
0
0
0
0
0
8
8
0
8
0
% T
% Val:
0
0
70
0
8
0
0
0
0
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
8
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _