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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
JAG1
All Species:
31.21
Human Site:
Y1176
Identified Species:
57.22
UniProt:
P78504
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78504
NP_000205.1
1218
133799
Y1176
R
F
A
K
Q
P
A
Y
T
L
V
D
R
E
E
Chimpanzee
Pan troglodytes
XP_001169666
1218
133732
Y1176
R
F
A
K
Q
P
A
Y
T
L
V
D
R
E
E
Rhesus Macaque
Macaca mulatta
XP_001116216
1220
134468
Y1178
R
F
A
K
Q
P
A
Y
T
L
V
D
R
E
E
Dog
Lupus familis
XP_542892
1218
133767
Y1176
R
F
A
K
Q
P
A
Y
T
L
V
D
R
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXX0
1218
134146
Y1176
R
F
A
K
Q
P
V
Y
T
L
V
D
R
E
E
Rat
Rattus norvegicus
Q63722
1219
134308
Y1177
R
F
A
K
Q
P
V
Y
T
L
V
D
R
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514910
1426
156076
Y1384
R
F
A
K
Q
P
A
Y
T
L
V
D
R
D
E
Chicken
Gallus gallus
XP_415035
1311
143036
Y1269
R
F
A
K
Q
P
A
Y
T
L
V
D
R
D
E
Frog
Xenopus laevis
P21783
2524
275106
M2225
P
F
Q
Q
S
P
S
M
P
L
N
H
L
T
S
Zebra Danio
Brachydanio rerio
Q90Y54
1213
133348
K1171
L
Q
K
A
R
F
T
K
Q
P
A
Y
T
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18168
1404
150325
H1354
R
S
S
Q
I
L
L
H
K
T
Q
N
S
D
M
Honey Bee
Apis mellifera
XP_394560
1331
142847
H1271
M
V
S
D
E
S
R
H
R
L
P
P
L
Y
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
V1023
H
L
C
D
G
E
E
V
L
Y
T
T
W
I
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.6
97.4
N.A.
96.5
96.3
N.A.
73.8
81.2
20.5
74.3
N.A.
30.7
38.6
N.A.
28.8
Protein Similarity:
100
99.6
98.1
98.7
N.A.
98
97.6
N.A.
79
86.5
31.8
84.6
N.A.
46.3
53.7
N.A.
41.7
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
20
0
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
33.3
6.6
N.A.
40
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
62
8
0
0
47
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
0
0
0
0
0
0
0
62
0
24
0
% D
% Glu:
0
0
0
0
8
8
8
0
0
0
0
0
0
47
62
% E
% Phe:
0
70
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
16
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
8
62
0
0
0
8
8
0
0
0
0
0
8
% K
% Leu:
8
8
0
0
0
8
8
0
8
77
0
0
16
8
0
% L
% Met:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% N
% Pro:
8
0
0
0
0
70
0
0
8
8
8
8
0
0
0
% P
% Gln:
0
8
8
16
62
0
0
0
8
0
8
0
0
0
0
% Q
% Arg:
70
0
0
0
8
0
8
0
8
0
0
0
62
0
0
% R
% Ser:
0
8
16
0
8
8
8
0
0
0
0
0
8
0
8
% S
% Thr:
0
0
0
0
0
0
8
0
62
8
8
8
8
8
0
% T
% Val:
0
8
0
0
0
0
16
8
0
0
62
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
8
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _