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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ10
All Species:
29.7
Human Site:
S299
Identified Species:
72.59
UniProt:
P78508
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78508
NP_002232.2
379
42508
S299
A
T
C
Q
V
R
T
S
Y
L
P
E
E
I
L
Chimpanzee
Pan troglodytes
XP_513920
628
69490
S548
A
T
C
Q
V
R
T
S
Y
L
P
E
E
I
L
Rhesus Macaque
Macaca mulatta
XP_001115293
615
68086
S535
A
T
C
Q
V
R
T
S
Y
L
P
E
E
I
L
Dog
Lupus familis
XP_545752
660
72375
S580
A
T
C
Q
V
R
T
S
Y
L
P
E
E
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM63
379
42414
S299
A
T
C
Q
V
R
T
S
Y
L
P
E
E
I
L
Rat
Rattus norvegicus
P49655
379
42462
S299
A
T
C
Q
V
R
T
S
Y
L
P
E
E
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509904
569
64097
S490
S
T
S
A
V
C
Q
S
R
T
S
Y
I
P
E
Chicken
Gallus gallus
P52186
427
48500
S313
A
M
T
T
Q
C
R
S
S
Y
L
A
N
E
I
Frog
Xenopus laevis
NP_001088081
378
42640
S299
A
T
C
Q
V
R
T
S
Y
L
P
E
E
I
L
Zebra Danio
Brachydanio rerio
XP_001342993
425
47220
T322
T
V
E
P
T
S
A
T
C
Q
V
R
T
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.3
61.6
56.5
N.A.
99.2
98.1
N.A.
44.2
37.9
82
64.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.3
61.6
56.9
N.A.
99.4
98.6
N.A.
53.9
56.9
92.3
77.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
20
13.3
100
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
20
100
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
0
0
10
0
0
10
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
70
0
0
20
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
70
70
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
70
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
70
10
0
0
0
70
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
70
0
0
10
0
% P
% Gln:
0
0
0
70
10
0
10
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
70
10
0
10
0
0
10
0
0
0
% R
% Ser:
10
0
10
0
0
10
0
90
10
0
10
0
0
10
0
% S
% Thr:
10
80
10
10
10
0
70
10
0
10
0
0
10
0
0
% T
% Val:
0
10
0
0
80
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
70
10
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _