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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RELN All Species: 18.18
Human Site: S718 Identified Species: 57.14
UniProt: P78509 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78509 NP_774959.1 3460 388417 S718 I S E S F G S S R L S S Y H N
Chimpanzee Pan troglodytes XP_519291 3459 388225 S717 I S E S F G S S R L S S Y H N
Rhesus Macaque Macaca mulatta XP_001087945 3460 388546 S718 I S E S F G S S R L S S Y H N
Dog Lupus familis XP_849464 3474 389557 S732 I S E S F G S S R L S S Y H N
Cat Felis silvestris
Mouse Mus musculus Q60841 3461 387495 A719 I S E S F G S A R L S S Y H N
Rat Rattus norvegicus P58751 3462 387513 S720 I S E S F G S S R L S S Y H N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O93574 3209 361265 P569 S Y L N Y H E P R I I S V E L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784287 1620 181379
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 98.9 96.3 N.A. 94.8 94.9 N.A. N.A. 83.7 N.A. N.A. N.A. N.A. N.A. N.A. 21.7
Protein Similarity: 100 98.5 99.5 98.4 N.A. 98 98.3 N.A. N.A. 89 N.A. N.A. N.A. N.A. N.A. N.A. 31
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 33.3 N.A. N.A. N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 75 0 0 0 13 0 0 0 0 0 0 13 0 % E
% Phe: 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 13 0 0 0 0 0 0 0 75 0 % H
% Ile: 75 0 0 0 0 0 0 0 0 13 13 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 13 0 0 0 0 0 0 75 0 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 75 % N
% Pro: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 88 0 0 0 0 0 0 % R
% Ser: 13 75 0 75 0 0 75 63 0 0 75 88 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 13 0 0 13 0 0 0 0 0 0 0 75 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _