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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPX All Species: 21.52
Human Site: Y77 Identified Species: 67.62
UniProt: P78539 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78539 NP_006298.1 464 51572 Y77 R A P Q G G Y Y K T A L G T R
Chimpanzee Pan troglodytes Q864W0 764 85494 S78 V Q T R T C R S T G S W S T L
Rhesus Macaque Macaca mulatta XP_001084091 468 52021 Y81 R A P Q G G Y Y K T A L G T R
Dog Lupus familis XP_548948 462 51037 Y75 R A P Q G G Y Y K T A L G T R
Cat Felis silvestris
Mouse Mus musculus Q9R0M3 464 51555 Y77 R A P P G G Y Y K T A L G T R
Rat Rattus norvegicus Q63769 464 51541 Y77 R A P P G G Y Y K T A L G T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513542 418 46422 C57 H G S S Q L I C Q S N K R W S
Chicken Gallus gallus
Frog Xenopus laevis Q6GP28 458 51436 Y72 Y S P L G P R Y R S T L G T R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21 98.2 89.4 N.A. 92.6 93 N.A. 78 N.A. 40.2 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 33.1 98.2 90.7 N.A. 95 95.4 N.A. 83.8 N.A. 59.7 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. 0 N.A. 46.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 93.3 93.3 N.A. 13.3 N.A. 66.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 63 0 0 0 0 0 0 0 0 63 0 0 0 0 % A
% Cys: 0 0 0 0 0 13 0 13 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 13 0 0 75 63 0 0 0 13 0 0 75 0 0 % G
% His: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 63 0 0 13 0 0 0 % K
% Leu: 0 0 0 13 0 13 0 0 0 0 0 75 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % N
% Pro: 0 0 75 25 0 13 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 13 0 38 13 0 0 0 13 0 0 0 0 0 0 % Q
% Arg: 63 0 0 13 0 0 25 0 13 0 0 0 13 0 75 % R
% Ser: 0 13 13 13 0 0 0 13 0 25 13 0 13 0 13 % S
% Thr: 0 0 13 0 13 0 0 0 13 63 13 0 0 88 0 % T
% Val: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 13 0 13 0 % W
% Tyr: 13 0 0 0 0 0 63 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _