Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARG2 All Species: 9.7
Human Site: S60 Identified Species: 19.39
UniProt: P78540 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78540 NP_001163.1 354 38578 S60 G L M K R L S S L G C H L K D
Chimpanzee Pan troglodytes XP_001137493 409 44101 R115 R A E P L P W R F S V L R I M
Rhesus Macaque Macaca mulatta XP_001107412 354 38526 S60 G L M K R L S S L G C H L K D
Dog Lupus familis XP_537488 354 38491 S60 G L M K R L S S L G C Q L K D
Cat Felis silvestris
Mouse Mus musculus O08691 354 38860 R60 G L L K R L S R L G C H L K D
Rat Rattus norvegicus O08701 354 38622 M60 G L L K R L S M L G C H I K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505820 324 34437 Q43 L I E K L E A Q G C D V K D Y
Chicken Gallus gallus
Frog Xenopus laevis Q91553 360 39137 N62 G L I E R L S N L G C N V C D
Zebra Danio Brachydanio rerio NP_955905 347 37756 S59 A G L V E R L S N L D Y P V H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791131 346 37687 G51 G H S V I D H G D L V F P A G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P00812 333 35643 W52 T S I E D L G W S T E L E P S
Red Bread Mold Neurospora crassa P33280 358 38246 F56 L G I V A V G F S G G Q C K P
Conservation
Percent
Protein Identity: 100 69.9 98.8 93.7 N.A. 84.7 83.9 N.A. 53.6 N.A. 72.2 61.2 N.A. N.A. N.A. N.A. 42.6
Protein Similarity: 100 70.4 99.1 96.6 N.A. 91.8 91.8 N.A. 67.2 N.A. 85 79.9 N.A. N.A. N.A. N.A. 64.1
P-Site Identity: 100 0 100 93.3 N.A. 86.6 80 N.A. 6.6 N.A. 60 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 0 100 93.3 N.A. 93.3 93.3 N.A. 20 N.A. 93.3 20 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.7 41.9
Protein Similarity: N.A. N.A. N.A. N.A. 48 58.3
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 9 0 9 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 50 0 9 9 0 % C
% Asp: 0 0 0 0 9 9 0 0 9 0 17 0 0 9 50 % D
% Glu: 0 0 17 17 9 9 0 0 0 0 9 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 9 0 0 9 0 0 0 % F
% Gly: 59 17 0 0 0 0 17 9 9 59 9 0 0 0 9 % G
% His: 0 9 0 0 0 0 9 0 0 0 0 34 0 0 9 % H
% Ile: 0 9 25 0 9 0 0 0 0 0 0 0 9 9 0 % I
% Lys: 0 0 0 50 0 0 0 0 0 0 0 0 9 50 0 % K
% Leu: 17 50 25 0 17 59 9 0 50 17 0 17 34 0 0 % L
% Met: 0 0 25 0 0 0 0 9 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 9 9 0 0 9 0 0 0 % N
% Pro: 0 0 0 9 0 9 0 0 0 0 0 0 17 9 9 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 17 0 0 0 % Q
% Arg: 9 0 0 0 50 9 0 17 0 0 0 0 9 0 0 % R
% Ser: 0 9 9 0 0 0 50 34 17 9 0 0 0 0 9 % S
% Thr: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % T
% Val: 0 0 0 25 0 9 0 0 0 0 17 9 9 9 0 % V
% Trp: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _