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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARG2
All Species:
23.03
Human Site:
Y216
Identified Species:
46.06
UniProt:
P78540
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78540
NP_001163.1
354
38578
Y216
L
K
N
Y
D
I
Q
Y
F
S
M
R
D
I
D
Chimpanzee
Pan troglodytes
XP_001137493
409
44101
T271
D
A
H
A
D
I
N
T
P
L
T
T
S
S
G
Rhesus Macaque
Macaca mulatta
XP_001107412
354
38526
Y216
L
K
N
Y
D
I
Q
Y
F
S
M
R
D
I
D
Dog
Lupus familis
XP_537488
354
38491
Y216
L
K
N
Y
D
I
Q
Y
F
S
M
R
D
I
D
Cat
Felis silvestris
Mouse
Mus musculus
O08691
354
38860
Y216
L
K
N
Y
D
I
Q
Y
F
S
M
R
E
I
D
Rat
Rattus norvegicus
O08701
354
38622
Y216
L
K
S
F
D
I
Q
Y
F
S
M
R
D
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505820
324
34437
C188
D
V
D
P
G
E
H
C
I
V
K
N
L
G
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91553
360
39137
Y218
L
K
N
Y
D
I
S
Y
Y
S
M
R
H
I
D
Zebra Danio
Brachydanio rerio
NP_955905
347
37756
L211
E
H
V
F
L
K
T
L
G
I
Q
Y
F
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791131
346
37687
I198
L
E
K
H
G
I
K
I
F
S
I
H
E
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P00812
333
35643
A197
N
L
S
P
K
K
I
A
Y
I
G
L
R
D
V
Red Bread Mold
Neurospora crassa
P33280
358
38246
L218
G
W
L
K
P
D
H
L
L
S
V
K
K
L
V
Conservation
Percent
Protein Identity:
100
69.9
98.8
93.7
N.A.
84.7
83.9
N.A.
53.6
N.A.
72.2
61.2
N.A.
N.A.
N.A.
N.A.
42.6
Protein Similarity:
100
70.4
99.1
96.6
N.A.
91.8
91.8
N.A.
67.2
N.A.
85
79.9
N.A.
N.A.
N.A.
N.A.
64.1
P-Site Identity:
100
13.3
100
100
N.A.
93.3
86.6
N.A.
0
N.A.
80
0
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
6.6
N.A.
86.6
6.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.7
41.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48
58.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
17
0
9
0
59
9
0
0
0
0
0
0
34
9
50
% D
% Glu:
9
9
0
0
0
9
0
0
0
0
0
0
17
0
0
% E
% Phe:
0
0
0
17
0
0
0
0
50
0
0
0
9
0
0
% F
% Gly:
9
0
0
0
17
0
0
0
9
0
9
0
0
9
9
% G
% His:
0
9
9
9
0
0
17
0
0
0
0
9
9
0
0
% H
% Ile:
0
0
0
0
0
67
9
9
9
17
9
0
0
50
9
% I
% Lys:
0
50
9
9
9
17
9
0
0
0
9
9
9
0
0
% K
% Leu:
59
9
9
0
9
0
0
17
9
9
0
9
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
9
% M
% Asn:
9
0
42
0
0
0
9
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
17
9
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
42
0
0
0
9
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
50
9
0
0
% R
% Ser:
0
0
17
0
0
0
9
0
0
67
0
0
9
17
0
% S
% Thr:
0
0
0
0
0
0
9
9
0
0
9
9
0
0
0
% T
% Val:
0
9
9
0
0
0
0
0
0
9
9
0
0
9
17
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
42
0
0
0
50
17
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _