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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARG2
All Species:
26.67
Human Site:
Y278
Identified Species:
53.33
UniProt:
P78540
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78540
NP_001163.1
354
38578
Y278
L
T
Y
R
E
G
M
Y
I
A
E
E
I
H
N
Chimpanzee
Pan troglodytes
XP_001137493
409
44101
Y333
E
H
F
I
L
K
N
Y
D
I
Q
Y
F
S
M
Rhesus Macaque
Macaca mulatta
XP_001107412
354
38526
Y278
L
T
Y
R
E
G
M
Y
I
A
E
E
I
H
N
Dog
Lupus familis
XP_537488
354
38491
Y278
L
T
Y
R
E
G
M
Y
I
T
E
E
I
H
N
Cat
Felis silvestris
Mouse
Mus musculus
O08691
354
38860
Y278
L
T
Y
R
E
G
V
Y
I
T
E
E
I
H
N
Rat
Rattus norvegicus
O08701
354
38622
Y278
L
T
Y
R
E
G
L
Y
I
T
E
E
I
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505820
324
34437
P249
P
A
T
G
T
P
V
P
G
G
L
S
Y
R
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91553
360
39137
Y280
L
T
Y
R
E
G
V
Y
I
T
E
E
I
H
N
Zebra Danio
Brachydanio rerio
NP_955905
347
37756
Y272
P
V
N
G
G
L
T
Y
R
E
G
I
Y
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791131
346
37687
Y260
L
T
Y
R
E
G
I
Y
I
A
E
E
I
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P00812
333
35643
D258
I
M
C
S
Y
D
V
D
G
V
D
P
L
Y
I
Red Bread Mold
Neurospora crassa
P33280
358
38246
A283
H
L
S
F
D
V
D
A
L
D
P
M
W
A
P
Conservation
Percent
Protein Identity:
100
69.9
98.8
93.7
N.A.
84.7
83.9
N.A.
53.6
N.A.
72.2
61.2
N.A.
N.A.
N.A.
N.A.
42.6
Protein Similarity:
100
70.4
99.1
96.6
N.A.
91.8
91.8
N.A.
67.2
N.A.
85
79.9
N.A.
N.A.
N.A.
N.A.
64.1
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
80
N.A.
0
N.A.
86.6
6.6
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
20
100
93.3
N.A.
93.3
93.3
N.A.
6.6
N.A.
93.3
6.6
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.7
41.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48
58.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
9
0
25
0
0
0
17
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
9
9
9
9
9
9
0
0
0
0
% D
% Glu:
9
0
0
0
59
0
0
0
0
9
59
59
0
0
17
% E
% Phe:
0
0
9
9
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
17
9
59
0
0
17
9
9
0
0
0
0
% G
% His:
9
9
0
0
0
0
0
0
0
0
0
0
0
50
0
% H
% Ile:
9
0
0
9
0
0
9
0
59
9
0
9
59
9
9
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
59
9
0
0
9
9
9
0
9
0
9
0
9
0
0
% L
% Met:
0
9
0
0
0
0
25
0
0
0
0
9
0
0
9
% M
% Asn:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
42
% N
% Pro:
17
0
0
0
0
9
0
9
0
0
9
9
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
59
0
0
0
0
9
0
0
0
0
9
0
% R
% Ser:
0
0
9
9
0
0
0
0
0
0
0
9
0
9
9
% S
% Thr:
0
59
9
0
9
0
9
0
0
34
0
0
0
0
9
% T
% Val:
0
9
0
0
0
9
34
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
59
0
9
0
0
75
0
0
0
9
17
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _