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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NTHL1
All Species:
30.3
Human Site:
S135
Identified Species:
51.28
UniProt:
P78549
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78549
NP_002519.1
312
34390
S135
R
R
Y
Q
V
L
L
S
L
M
L
S
S
Q
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082772
312
34406
S135
R
R
Y
Q
V
L
L
S
L
M
L
S
S
Q
T
Dog
Lupus familis
XP_853674
312
34244
S135
Q
R
Y
Q
V
L
L
S
L
M
L
S
S
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
O35980
300
33628
S123
R
R
Y
Q
V
L
L
S
L
M
L
S
S
Q
T
Rat
Rattus norvegicus
O70249
345
38693
S115
Q
L
Y
S
H
W
A
S
V
D
S
H
F
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517653
262
28773
R111
G
V
E
Q
C
F
D
R
D
A
P
P
E
V
Q
Chicken
Gallus gallus
NP_001073043
281
31866
S104
M
R
Y
Q
V
L
L
S
L
M
L
S
S
Q
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001346643
430
48207
S173
R
R
Y
Q
V
L
I
S
L
M
L
S
S
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610078
388
43493
A202
Q
R
F
Q
N
L
V
A
L
M
L
S
S
Q
T
Honey Bee
Apis mellifera
XP_623602
321
36892
A136
A
R
Y
Q
S
L
I
A
L
M
L
S
S
Q
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793669
395
44330
S198
Y
R
Y
H
V
L
L
S
L
M
L
S
S
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151454
364
40315
T168
R
F
A
V
L
I
S
T
M
M
S
S
Q
T
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001077988
377
41467
A178
R
F
A
V
L
L
G
A
L
L
S
S
Q
T
K
Baker's Yeast
Sacchar. cerevisiae
P31378
399
45558
D158
M
L
S
S
Q
T
K
D
E
V
T
A
M
A
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.9
79.4
N.A.
78.8
20.8
N.A.
50.9
63.4
N.A.
42.7
N.A.
40.7
46.1
N.A.
43.5
Protein Similarity:
100
N.A.
95.5
86.2
N.A.
84.9
33
N.A.
60.5
73.4
N.A.
52.3
N.A.
53
59.5
N.A.
56.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
20
N.A.
6.6
93.3
N.A.
93.3
N.A.
66.6
73.3
N.A.
86.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
40
N.A.
6.6
93.3
N.A.
100
N.A.
93.3
86.6
N.A.
86.6
Percent
Protein Identity:
N.A.
38.7
N.A.
38.4
31
N.A.
Protein Similarity:
N.A.
53.3
N.A.
52.5
43.8
N.A.
P-Site Identity:
N.A.
20
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
0
0
8
22
0
8
0
8
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
8
8
8
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
0
% E
% Phe:
0
15
8
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
8
15
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
15
% K
% Leu:
0
15
0
0
15
72
43
0
72
8
65
0
0
0
0
% L
% Met:
15
0
0
0
0
0
0
0
8
72
0
0
8
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% P
% Gln:
22
0
0
65
8
0
0
0
0
0
0
0
15
72
8
% Q
% Arg:
43
65
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
15
8
0
8
58
0
0
22
79
65
0
8
% S
% Thr:
0
0
0
0
0
8
0
8
0
0
8
0
0
15
65
% T
% Val:
0
8
0
15
50
0
8
0
8
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
65
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _