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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NTHL1
All Species:
13.94
Human Site:
S22
Identified Species:
23.59
UniProt:
P78549
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78549
NP_002519.1
312
34390
S22
R
M
L
T
R
S
R
S
L
G
P
G
A
G
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082772
312
34406
S22
R
M
L
T
R
N
R
S
L
G
P
R
A
G
P
Dog
Lupus familis
XP_853674
312
34244
S22
R
M
M
T
R
S
R
S
W
G
P
G
A
A
P
Cat
Felis silvestris
Mouse
Mus musculus
O35980
300
33628
G22
A
T
R
I
A
S
E
G
C
R
E
E
L
A
P
Rat
Rattus norvegicus
O70249
345
38693
P29
L
W
A
S
I
P
C
P
R
S
E
L
R
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517653
262
28773
P22
E
K
G
R
Q
T
P
P
D
T
S
P
F
A
V
Chicken
Gallus gallus
NP_001073043
281
31866
G22
R
L
G
A
A
T
A
G
S
R
V
P
S
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001346643
430
48207
S32
A
T
E
T
M
G
K
S
T
I
N
K
D
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610078
388
43493
P23
K
R
G
D
L
I
K
P
T
E
I
K
S
R
P
Honey Bee
Apis mellifera
XP_623602
321
36892
N25
R
S
E
N
K
D
H
N
K
D
I
S
T
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793669
395
44330
S76
K
L
S
S
A
S
I
S
D
P
P
E
N
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151454
364
40315
N34
R
L
L
V
R
A
D
N
S
P
V
A
R
E
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001077988
377
41467
T44
S
K
H
I
S
L
K
T
Q
H
P
L
S
D
S
Baker's Yeast
Sacchar. cerevisiae
P31378
399
45558
T23
R
P
L
V
K
T
E
T
G
P
E
S
E
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.9
79.4
N.A.
78.8
20.8
N.A.
50.9
63.4
N.A.
42.7
N.A.
40.7
46.1
N.A.
43.5
Protein Similarity:
100
N.A.
95.5
86.2
N.A.
84.9
33
N.A.
60.5
73.4
N.A.
52.3
N.A.
53
59.5
N.A.
56.9
P-Site Identity:
100
N.A.
86.6
80
N.A.
13.3
0
N.A.
0
6.6
N.A.
20
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
13.3
6.6
N.A.
13.3
26.6
N.A.
26.6
N.A.
26.6
20
N.A.
40
Percent
Protein Identity:
N.A.
38.7
N.A.
38.4
31
N.A.
Protein Similarity:
N.A.
53.3
N.A.
52.5
43.8
N.A.
P-Site Identity:
N.A.
20
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
40
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
8
22
8
8
0
0
0
0
8
22
29
8
% A
% Cys:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
8
0
15
8
0
0
8
8
8
% D
% Glu:
8
0
15
0
0
0
15
0
0
8
22
15
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
22
0
0
8
0
15
8
22
0
15
0
22
0
% G
% His:
0
0
8
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
15
8
8
8
0
0
8
15
0
0
0
15
% I
% Lys:
15
15
0
0
15
0
22
0
8
0
0
15
0
0
0
% K
% Leu:
8
22
29
0
8
8
0
0
15
0
0
15
8
15
8
% L
% Met:
0
22
8
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
15
0
0
8
0
8
0
0
% N
% Pro:
0
8
0
0
0
8
8
22
0
22
36
15
0
0
36
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
50
8
8
8
29
0
22
0
8
15
0
8
15
8
0
% R
% Ser:
8
8
8
15
8
29
0
36
15
8
8
15
22
8
8
% S
% Thr:
0
15
0
29
0
22
0
15
15
8
0
0
8
8
8
% T
% Val:
0
0
0
15
0
0
0
0
0
0
15
0
0
0
8
% V
% Trp:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _