KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NTHL1
All Species:
6.97
Human Site:
S71
Identified Species:
11.79
UniProt:
P78549
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78549
NP_002519.1
312
34390
S71
L
R
V
A
Y
E
G
S
D
S
E
K
G
E
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082772
312
34406
S71
L
C
V
A
Y
E
G
S
D
S
E
K
G
E
K
Dog
Lupus familis
XP_853674
312
34244
P71
L
K
V
A
Y
E
A
P
G
H
E
K
G
E
S
Cat
Felis silvestris
Mouse
Mus musculus
O35980
300
33628
A59
T
H
V
A
Y
E
A
A
N
G
E
E
G
E
D
Rat
Rattus norvegicus
O70249
345
38693
W64
G
V
L
A
D
Q
V
W
T
L
T
Q
T
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517653
262
28773
L59
L
E
V
C
Y
E
P
L
A
G
S
G
G
E
A
Chicken
Gallus gallus
NP_001073043
281
31866
E59
P
G
P
K
W
E
P
E
N
W
Q
Q
Q
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001346643
430
48207
E95
N
T
T
S
K
M
K
E
E
P
D
Q
A
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610078
388
43493
T77
N
G
E
A
V
K
K
T
N
I
K
M
E
P
L
Honey Bee
Apis mellifera
XP_623602
321
36892
E75
N
K
I
E
N
L
Q
E
D
T
I
K
E
D
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793669
395
44330
T128
A
S
V
S
K
R
E
T
S
T
D
C
A
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151454
364
40315
H76
L
E
V
N
G
Q
H
H
K
K
Q
V
P
D
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001077988
377
41467
V87
E
K
Y
S
G
K
G
V
N
T
H
K
L
C
G
Baker's Yeast
Sacchar. cerevisiae
P31378
399
45558
G119
A
P
V
D
I
I
G
G
S
S
I
P
V
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.9
79.4
N.A.
78.8
20.8
N.A.
50.9
63.4
N.A.
42.7
N.A.
40.7
46.1
N.A.
43.5
Protein Similarity:
100
N.A.
95.5
86.2
N.A.
84.9
33
N.A.
60.5
73.4
N.A.
52.3
N.A.
53
59.5
N.A.
56.9
P-Site Identity:
100
N.A.
86.6
60
N.A.
46.6
13.3
N.A.
40
6.6
N.A.
0
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
86.6
66.6
N.A.
66.6
33.3
N.A.
40
33.3
N.A.
26.6
N.A.
33.3
40
N.A.
33.3
Percent
Protein Identity:
N.A.
38.7
N.A.
38.4
31
N.A.
Protein Similarity:
N.A.
53.3
N.A.
52.5
43.8
N.A.
P-Site Identity:
N.A.
13.3
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
43
0
0
15
8
8
0
0
0
15
0
8
% A
% Cys:
0
8
0
8
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
0
0
8
8
0
0
0
22
0
15
0
0
15
15
% D
% Glu:
8
15
8
8
0
43
8
22
8
0
29
8
15
43
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
15
0
0
15
0
29
8
8
15
0
8
36
0
15
% G
% His:
0
8
0
0
0
0
8
8
0
8
8
0
0
0
0
% H
% Ile:
0
0
8
0
8
8
0
0
0
8
15
0
0
0
15
% I
% Lys:
0
22
0
8
15
15
15
0
8
8
8
36
0
0
8
% K
% Leu:
36
0
8
0
0
8
0
8
0
8
0
0
8
15
15
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% M
% Asn:
22
0
0
8
8
0
0
0
29
0
0
0
0
0
0
% N
% Pro:
8
8
8
0
0
0
15
8
0
8
0
8
8
8
0
% P
% Gln:
0
0
0
0
0
15
8
0
0
0
15
22
8
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
22
0
0
0
15
15
22
8
0
0
0
15
% S
% Thr:
8
8
8
0
0
0
0
15
8
22
8
0
8
8
0
% T
% Val:
0
8
58
0
8
0
8
8
0
0
0
8
8
0
8
% V
% Trp:
0
0
0
0
8
0
0
8
0
8
0
0
0
0
0
% W
% Tyr:
0
0
8
0
36
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _