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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHEX
All Species:
24.55
Human Site:
S186
Identified Species:
49.09
UniProt:
P78562
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78562
NP_000435.3
749
86474
S186
V
W
S
E
R
K
F
S
L
L
Q
T
L
A
T
Chimpanzee
Pan troglodytes
XP_520972
749
86557
S186
V
W
S
E
R
K
F
S
L
L
Q
T
L
A
T
Rhesus Macaque
Macaca mulatta
XP_001087261
749
86532
S186
V
W
S
E
R
K
F
S
L
L
Q
T
L
A
T
Dog
Lupus familis
XP_537979
749
86353
S186
V
W
S
E
R
K
F
S
L
L
H
T
L
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P70669
749
86400
S186
V
W
S
E
R
K
F
S
L
L
Q
T
L
A
T
Rat
Rattus norvegicus
P0C1T0
774
89178
E211
E
T
M
G
P
K
W
E
L
E
R
Q
L
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513691
751
86657
S188
T
W
S
E
R
K
F
S
L
L
Q
T
L
A
A
Chicken
Gallus gallus
XP_416801
716
82946
S176
L
R
G
Q
Y
S
N
S
V
F
I
R
L
Y
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082818
458
53118
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392502
776
89056
S227
S
W
K
P
P
P
Y
S
V
E
V
L
L
G
R
Nematode Worm
Caenorhab. elegans
O16796
848
97043
N284
N
W
D
K
T
K
F
N
F
T
S
L
L
V
N
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
D211
R
W
N
E
T
D
F
D
F
V
W
L
L
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
98.6
95.1
N.A.
95.9
37.5
N.A.
88.5
78.2
N.A.
41.1
N.A.
N.A.
37.1
31.9
38.4
Protein Similarity:
100
98.5
100
97.4
N.A.
98.6
58.7
N.A.
94.9
87.8
N.A.
51.4
N.A.
N.A.
57.3
51.6
57.6
P-Site Identity:
100
100
100
86.6
N.A.
100
26.6
N.A.
86.6
13.3
N.A.
0
N.A.
N.A.
20
26.6
33.3
P-Site Similarity:
100
100
100
86.6
N.A.
100
40
N.A.
86.6
33.3
N.A.
0
N.A.
N.A.
33.3
40
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
59
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
9
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
59
0
0
0
9
0
17
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
67
0
17
9
0
0
0
0
0
% F
% Gly:
0
0
9
9
0
0
0
0
0
0
0
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
9
9
0
67
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
59
50
0
25
92
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
9
9
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
9
17
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
42
9
0
0
0
% Q
% Arg:
9
9
0
0
50
0
0
0
0
0
9
9
0
0
9
% R
% Ser:
9
0
50
0
0
9
0
67
0
0
9
0
0
0
0
% S
% Thr:
9
9
0
0
17
0
0
0
0
9
0
50
0
0
42
% T
% Val:
42
0
0
0
0
0
0
0
17
9
9
0
0
9
17
% V
% Trp:
0
75
0
0
0
0
9
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
9
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _