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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHEX
All Species:
35.76
Human Site:
S695
Identified Species:
71.52
UniProt:
P78562
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78562
NP_000435.3
749
86474
S695
Y
A
H
V
R
C
N
S
Y
R
P
E
A
A
R
Chimpanzee
Pan troglodytes
XP_520972
749
86557
S695
Y
A
H
V
R
C
N
S
Y
R
P
E
A
A
R
Rhesus Macaque
Macaca mulatta
XP_001087261
749
86532
S695
Y
A
H
V
R
C
N
S
Y
R
P
E
A
A
R
Dog
Lupus familis
XP_537979
749
86353
S695
Y
A
H
V
R
C
N
S
Y
R
P
E
A
A
R
Cat
Felis silvestris
Mouse
Mus musculus
P70669
749
86400
S695
Y
A
H
V
R
C
N
S
Y
R
P
E
A
A
R
Rat
Rattus norvegicus
P0C1T0
774
89178
S721
Y
A
Q
V
W
C
G
S
Y
R
P
E
F
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513691
751
86657
S697
Y
A
H
V
R
C
N
S
Y
R
P
E
A
A
R
Chicken
Gallus gallus
XP_416801
716
82946
S662
Y
A
H
V
R
C
N
S
F
R
S
E
S
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082818
458
53118
I405
Y
S
S
S
T
N
Q
I
R
F
P
A
G
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392502
776
89056
S723
Y
A
Q
I
W
C
G
S
M
R
P
E
D
A
L
Nematode Worm
Caenorhab. elegans
O16796
848
97043
K795
Y
A
H
F
W
C
G
K
K
K
E
A
A
A
M
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
S710
F
A
Q
V
W
C
S
S
F
R
P
E
G
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
98.6
95.1
N.A.
95.9
37.5
N.A.
88.5
78.2
N.A.
41.1
N.A.
N.A.
37.1
31.9
38.4
Protein Similarity:
100
98.5
100
97.4
N.A.
98.6
58.7
N.A.
94.9
87.8
N.A.
51.4
N.A.
N.A.
57.3
51.6
57.6
P-Site Identity:
100
100
100
100
N.A.
100
66.6
N.A.
100
80
N.A.
13.3
N.A.
N.A.
53.3
40
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
66.6
N.A.
100
93.3
N.A.
20
N.A.
N.A.
60
46.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
92
0
0
0
0
0
0
0
0
0
17
59
84
0
% A
% Cys:
0
0
0
0
0
92
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
84
0
9
0
% E
% Phe:
9
0
0
9
0
0
0
0
17
9
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
25
0
0
0
0
0
17
0
0
% G
% His:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
9
9
9
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
17
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
9
59
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% P
% Gln:
0
0
25
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
59
0
0
0
9
84
0
0
0
0
59
% R
% Ser:
0
9
9
9
0
0
9
84
0
0
9
0
9
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
92
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _