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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHEX
All Species:
19.39
Human Site:
S8
Identified Species:
38.79
UniProt:
P78562
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78562
NP_000435.3
749
86474
S8
M
E
A
E
T
G
S
S
V
E
T
G
K
K
A
Chimpanzee
Pan troglodytes
XP_520972
749
86557
S8
M
E
A
E
T
G
S
S
V
E
T
G
K
K
A
Rhesus Macaque
Macaca mulatta
XP_001087261
749
86532
S8
M
E
A
E
T
G
S
S
V
E
T
G
K
R
A
Dog
Lupus familis
XP_537979
749
86353
S8
M
E
T
E
M
G
S
S
A
E
T
G
K
T
A
Cat
Felis silvestris
Mouse
Mus musculus
P70669
749
86400
T8
M
E
A
E
T
G
S
T
M
E
T
G
K
G
T
Rat
Rattus norvegicus
P0C1T0
774
89178
G39
L
L
T
L
L
L
M
G
A
I
V
T
L
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513691
751
86657
S10
A
E
A
A
Q
K
A
S
L
G
T
G
K
K
S
Chicken
Gallus gallus
XP_416801
716
82946
R10
G
E
T
V
P
A
S
R
R
A
A
N
K
A
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082818
458
53118
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392502
776
89056
R56
V
L
Q
H
P
G
N
R
R
K
S
L
G
I
T
Nematode Worm
Caenorhab. elegans
O16796
848
97043
A115
H
A
T
Q
T
E
H
A
G
F
G
D
P
T
E
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
I37
I
T
R
N
L
V
V
I
V
V
V
L
A
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
98.6
95.1
N.A.
95.9
37.5
N.A.
88.5
78.2
N.A.
41.1
N.A.
N.A.
37.1
31.9
38.4
Protein Similarity:
100
98.5
100
97.4
N.A.
98.6
58.7
N.A.
94.9
87.8
N.A.
51.4
N.A.
N.A.
57.3
51.6
57.6
P-Site Identity:
100
100
93.3
73.3
N.A.
73.3
0
N.A.
46.6
20
N.A.
0
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
6.6
N.A.
66.6
20
N.A.
0
N.A.
N.A.
33.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
42
9
0
9
9
9
17
9
9
0
9
9
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
59
0
42
0
9
0
0
0
42
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
50
0
9
9
9
9
50
9
17
0
% G
% His:
9
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
9
0
9
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
9
0
0
59
25
0
% K
% Leu:
9
17
0
9
17
9
0
0
9
0
0
17
9
9
9
% L
% Met:
42
0
0
0
9
0
9
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
17
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
9
9
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
0
17
17
0
0
0
0
9
0
% R
% Ser:
0
0
0
0
0
0
50
42
0
0
9
0
0
0
9
% S
% Thr:
0
9
34
0
42
0
0
9
0
0
50
9
0
17
25
% T
% Val:
9
0
0
9
0
9
9
0
34
9
17
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _