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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHEX
All Species:
41.52
Human Site:
Y657
Identified Species:
83.03
UniProt:
P78562
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78562
NP_000435.3
749
86474
Y657
L
R
E
A
F
R
A
Y
R
K
W
I
N
D
R
Chimpanzee
Pan troglodytes
XP_520972
749
86557
Y657
L
R
E
A
F
R
A
Y
R
K
W
I
N
D
R
Rhesus Macaque
Macaca mulatta
XP_001087261
749
86532
Y657
L
R
E
A
F
R
A
Y
R
K
W
I
N
D
R
Dog
Lupus familis
XP_537979
749
86353
Y657
L
R
E
A
F
R
A
Y
R
K
W
I
N
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P70669
749
86400
Y657
L
R
E
A
F
R
A
Y
R
K
W
I
N
D
R
Rat
Rattus norvegicus
P0C1T0
774
89178
Y686
V
R
Q
A
Y
K
A
Y
L
Q
W
L
A
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513691
751
86657
Y659
L
R
E
A
F
R
A
Y
R
K
W
I
S
D
E
Chicken
Gallus gallus
XP_416801
716
82946
Y624
L
R
E
A
F
R
A
Y
R
R
W
I
R
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082818
458
53118
Q372
Q
T
L
K
F
I
A
Q
S
D
I
G
W
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392502
776
89056
Y688
L
K
Q
S
F
R
A
Y
K
K
W
V
S
I
H
Nematode Worm
Caenorhab. elegans
O16796
848
97043
Y759
V
K
E
A
F
Q
A
Y
Q
K
Y
V
T
E
N
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
Y674
L
K
Q
A
F
R
A
Y
K
T
I
V
A
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
98.6
95.1
N.A.
95.9
37.5
N.A.
88.5
78.2
N.A.
41.1
N.A.
N.A.
37.1
31.9
38.4
Protein Similarity:
100
98.5
100
97.4
N.A.
98.6
58.7
N.A.
94.9
87.8
N.A.
51.4
N.A.
N.A.
57.3
51.6
57.6
P-Site Identity:
100
100
100
93.3
N.A.
100
33.3
N.A.
86.6
73.3
N.A.
20
N.A.
N.A.
46.6
40
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
93.3
93.3
N.A.
20
N.A.
N.A.
86.6
86.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
84
0
0
100
0
0
0
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
0
59
0
% D
% Glu:
0
0
67
0
0
0
0
0
0
0
0
0
0
25
9
% E
% Phe:
0
0
0
0
92
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
17
59
0
9
0
% I
% Lys:
0
25
0
9
0
9
0
0
17
67
0
0
0
0
17
% K
% Leu:
75
0
9
0
0
0
0
0
9
0
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
42
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
25
0
0
9
0
9
9
9
0
0
0
0
0
% Q
% Arg:
0
67
0
0
0
75
0
0
59
9
0
0
9
0
42
% R
% Ser:
0
0
0
9
0
0
0
0
9
0
0
0
17
0
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
9
0
0
9
0
9
% T
% Val:
17
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
75
0
9
0
0
% W
% Tyr:
0
0
0
0
9
0
0
92
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _