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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPLD1 All Species: 18.18
Human Site: Y246 Identified Species: 57.14
UniProt: P80108 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P80108 NP_001494.2 840 92336 Y246 L V E Q F Q E Y F L G G L D D
Chimpanzee Pan troglodytes XP_518268 842 92663 Y246 L V E Q F Q E Y F L G G L D D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535902 839 92443 Y246 L V E Q F Q E Y F L G G L D D
Cat Felis silvestris
Mouse Mus musculus O70362 837 93237 Y242 L V E Q F Q D Y F L G G L D D
Rat Rattus norvegicus Q8R2H5 843 93763 Y246 L V E Q F Q D Y F L G G L D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521465 622 68291 A63 K H Q D A Y Q A G S V Y P D S
Chicken Gallus gallus XP_418910 827 92076 G240 F H E Y F L G G V D D M A F W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001204395 503 54800
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 N.A. 83.6 N.A. 78.3 79.8 N.A. 50.8 61.5 N.A. N.A. N.A. N.A. N.A. N.A. 21.7
Protein Similarity: 100 97.7 N.A. 91.4 N.A. 87.3 88.6 N.A. 61.1 77 N.A. N.A. N.A. N.A. N.A. N.A. 35.1
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 6.6 13.3 N.A. N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 20 13.3 N.A. N.A. N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 13 0 0 13 0 0 0 0 13 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 13 0 0 25 0 0 13 13 0 0 75 63 % D
% Glu: 0 0 75 0 0 0 38 0 0 0 0 0 0 0 0 % E
% Phe: 13 0 0 0 75 0 0 0 63 0 0 0 0 13 0 % F
% Gly: 0 0 0 0 0 0 13 13 13 0 63 63 0 0 0 % G
% His: 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 63 0 0 0 0 13 0 0 0 63 0 0 63 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % P
% Gln: 0 0 13 63 0 63 13 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 13 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 63 0 0 0 0 0 0 13 0 13 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % W
% Tyr: 0 0 0 13 0 13 0 63 0 0 0 13 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _