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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCN2
All Species:
26.36
Human Site:
S178
Identified Species:
72.5
UniProt:
P80188
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P80188
NP_005555.2
198
22588
S178
N
F
I
R
F
S
K
S
L
G
L
P
E
N
H
Chimpanzee
Pan troglodytes
XP_520287
198
22623
S178
N
F
I
R
F
S
K
S
L
G
L
P
E
N
H
Rhesus Macaque
Macaca mulatta
XP_001083008
198
22429
S178
N
F
I
R
F
S
K
S
L
G
L
P
E
N
H
Dog
Lupus familis
XP_548441
198
22874
S178
E
F
I
R
F
A
K
S
I
G
L
T
E
D
H
Cat
Felis silvestris
Mouse
Mus musculus
P11672
200
22856
S180
R
F
T
R
F
A
K
S
L
G
L
K
D
D
N
Rat
Rattus norvegicus
P30152
198
22540
S178
R
F
V
S
F
A
K
S
L
G
L
K
D
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516011
215
23425
S201
N
F
I
E
F
A
K
S
Q
G
F
T
D
D
S
Chicken
Gallus gallus
P21760
178
20183
E156
I
F
R
K
L
A
R
E
R
N
Y
T
D
E
M
Frog
Xenopus laevis
NP_001086294
184
20998
T163
K
F
Q
S
F
A
K
T
Q
G
L
T
D
D
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
89.9
66.6
N.A.
61.5
63.1
N.A.
26
25.7
30.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
96.9
81.8
N.A.
79.5
77.2
N.A.
45.1
39.9
52.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
53.3
53.3
N.A.
46.6
6.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
66.6
33.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
56
45
0
% D
% Glu:
12
0
0
12
0
0
0
12
0
0
0
0
45
12
0
% E
% Phe:
0
100
0
0
89
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
89
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% H
% Ile:
12
0
56
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
12
0
0
12
0
0
89
0
0
0
0
23
0
0
0
% K
% Leu:
0
0
0
0
12
0
0
0
56
0
78
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
45
0
0
0
0
0
0
0
0
12
0
0
0
45
34
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
23
0
0
0
0
0
0
% Q
% Arg:
23
0
12
56
0
0
12
0
12
0
0
0
0
0
0
% R
% Ser:
0
0
0
23
0
34
0
78
0
0
0
0
0
0
12
% S
% Thr:
0
0
12
0
0
0
0
12
0
0
0
45
0
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _