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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K9
All Species:
15.15
Human Site:
S545
Identified Species:
30.3
UniProt:
P80192
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P80192
NP_149132.2
1104
121895
S545
K
R
K
S
L
I
N
S
R
S
S
P
P
A
S
Chimpanzee
Pan troglodytes
XP_001146659
1107
121909
S548
K
R
K
S
L
I
N
S
R
S
S
P
P
A
S
Rhesus Macaque
Macaca mulatta
XP_001083417
1104
121935
S545
K
R
K
S
L
I
N
S
R
S
S
P
P
A
S
Dog
Lupus familis
XP_547887
1216
135201
S657
K
R
K
S
L
I
N
S
R
S
S
P
P
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3U1V8
1077
118787
K506
R
K
S
R
L
K
L
K
D
G
N
R
I
S
L
Rat
Rattus norvegicus
Q66HA1
850
93091
T347
L
T
L
P
I
P
S
T
C
P
E
P
F
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7T2V3
1005
111856
K487
K
K
S
R
L
K
L
K
D
G
N
R
I
S
L
Zebra Danio
Brachydanio rerio
XP_689128
1009
111927
K496
R
V
Q
H
R
H
G
K
F
R
R
S
R
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95UN8
1161
128942
R517
R
H
T
I
T
A
V
R
D
K
A
E
Q
P
G
Honey Bee
Apis mellifera
XP_395037
1102
123539
L565
F
K
K
S
R
L
K
L
N
K
K
E
P
G
S
Nematode Worm
Caenorhab. elegans
O01700
928
103465
R412
Q
Y
P
S
T
V
T
R
D
H
G
G
P
K
S
Sea Urchin
Strong. purpuratus
XP_001195574
960
106888
E438
E
D
E
L
S
Q
A
E
I
Q
Q
K
L
H
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
99
81.4
N.A.
92.9
43
N.A.
N.A.
N.A.
53.8
58.9
N.A.
30.8
38.6
22.1
39.4
Protein Similarity:
100
98.1
99.5
84.2
N.A.
94.6
55.2
N.A.
N.A.
N.A.
66.4
69.4
N.A.
46
53.8
38.6
55.7
P-Site Identity:
100
100
100
100
N.A.
6.6
13.3
N.A.
N.A.
N.A.
13.3
0
N.A.
0
26.6
20
0
P-Site Similarity:
100
100
100
100
N.A.
33.3
33.3
N.A.
N.A.
N.A.
33.3
13.3
N.A.
13.3
40
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
0
0
0
9
0
0
42
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
34
0
0
0
0
0
0
% D
% Glu:
9
0
9
0
0
0
0
9
0
0
9
17
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
17
9
9
0
9
9
% G
% His:
0
9
0
9
0
9
0
0
0
9
0
0
0
9
0
% H
% Ile:
0
0
0
9
9
34
0
0
9
0
0
0
17
0
0
% I
% Lys:
42
25
42
0
0
17
9
25
0
17
9
9
0
9
9
% K
% Leu:
9
0
9
9
50
9
17
9
0
0
0
0
9
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
34
0
9
0
17
0
0
0
0
% N
% Pro:
0
0
9
9
0
9
0
0
0
9
0
42
50
9
0
% P
% Gln:
9
0
9
0
0
9
0
0
0
9
9
0
9
0
9
% Q
% Arg:
25
34
0
17
17
0
0
17
34
9
9
17
9
0
0
% R
% Ser:
0
0
17
50
9
0
9
34
0
34
34
9
0
17
50
% S
% Thr:
0
9
9
0
17
0
9
9
0
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
9
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _