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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IFI35 All Species: 7.27
Human Site: S226 Identified Species: 17.78
UniProt: P80217 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P80217 NP_005524.1 286 31514 S226 I Q K A E I R S Q P V P R S V
Chimpanzee Pan troglodytes XP_001158983 288 31879 S228 I Q K A E I R S Q P V P R S V
Rhesus Macaque Macaca mulatta XP_001112861 286 31664 L226 I Q N V E I R L Q P A P R S V
Dog Lupus familis XP_548077 286 31831 F226 I Q K A E I M F R P V P Q S V
Cat Felis silvestris
Mouse Mus musculus Q9D8C4 286 31857 F226 I Q K A E I K F Q Q A P H S V
Rat Rattus norvegicus NP_001009625 286 31746 F226 I Q E A E I K F Q Q A P H S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516056 98 10789 A51 T V L L S G V A D V M E E S T
Chicken Gallus gallus XP_418132 383 43329 P321 V T N L Q L Q P S H C T R T V
Frog Xenopus laevis NP_001088598 383 44113 T323 L N K L Q M F T G M S P K S V
Zebra Danio Brachydanio rerio XP_688060 371 42093 N305 I S E M K I S N S V C M R T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 91.6 74.1 N.A. 72 72.7 N.A. 20.6 33.1 22.4 29.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.2 95.8 83.9 N.A. 84.2 84.6 N.A. 26.2 51.1 42.8 48.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 73.3 73.3 N.A. 66.6 60 N.A. 6.6 13.3 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 73.3 86.6 N.A. 73.3 73.3 N.A. 20 46.6 60 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 50 0 0 0 10 0 0 30 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 20 0 60 0 0 0 0 0 0 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 10 30 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 20 0 0 % H
% Ile: 70 0 0 0 0 70 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 50 0 10 0 20 0 0 0 0 0 10 0 0 % K
% Leu: 10 0 10 30 0 10 0 10 0 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 10 10 0 0 10 10 10 0 0 0 % M
% Asn: 0 10 20 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 40 0 70 0 0 0 % P
% Gln: 0 60 0 0 20 0 10 0 50 20 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 30 0 10 0 0 0 50 0 0 % R
% Ser: 0 10 0 0 10 0 10 20 20 0 10 0 0 80 0 % S
% Thr: 10 10 0 0 0 0 0 10 0 0 0 10 0 20 10 % T
% Val: 10 10 0 10 0 0 10 0 0 20 30 0 0 0 90 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _