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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD11B2
All Species:
20.3
Human Site:
Y232
Identified Species:
40.61
UniProt:
P80365
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P80365
NP_000187.3
405
44127
Y232
P
Y
P
C
L
G
A
Y
G
T
S
K
A
A
V
Chimpanzee
Pan troglodytes
XP_523393
405
44092
Y232
P
Y
P
C
L
G
A
Y
G
T
S
K
A
A
V
Rhesus Macaque
Macaca mulatta
XP_001088119
491
53541
Y318
P
Y
P
C
L
G
A
Y
G
T
S
K
A
A
V
Dog
Lupus familis
XP_853935
323
35433
T163
A
M
A
L
L
M
D
T
F
S
C
E
L
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P51661
386
42168
Y226
S
P
A
G
D
M
P
Y
P
C
L
A
A
Y
G
Rat
Rattus norvegicus
P50233
400
43708
Y232
P
Y
P
C
L
A
A
Y
G
T
S
K
A
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512268
333
36740
P173
G
S
P
A
G
D
M
P
Y
P
C
L
A
A
Y
Chicken
Gallus gallus
Q5ZJZ5
339
38218
I179
T
K
A
F
L
P
L
I
R
R
S
K
G
R
V
Frog
Xenopus laevis
Q0IH28
323
35135
P163
A
L
T
K
A
L
L
P
S
M
I
K
N
R
R
Zebra Danio
Brachydanio rerio
Q566S6
309
33329
E149
S
V
Q
R
E
V
M
E
T
N
Y
F
G
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
Y166
L
K
V
M
V
V
N
Y
F
G
S
V
A
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130780
400
43694
Y232
P
Y
P
C
L
A
A
Y
G
T
S
K
A
A
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
81
70.1
N.A.
82.9
85.6
N.A.
58.2
25.6
21.4
22.7
N.A.
21.4
N.A.
N.A.
N.A.
Protein Similarity:
100
100
81.4
75.8
N.A.
88.8
90.6
N.A.
66.9
41.4
37.5
35.3
N.A.
35.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
13.3
86.6
N.A.
20
26.6
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
13.3
93.3
N.A.
20
26.6
6.6
6.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
85.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
90.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
25
9
9
17
42
0
0
0
0
9
67
50
0
% A
% Cys:
0
0
0
42
0
0
0
0
0
9
17
0
0
0
0
% C
% Asp:
0
0
0
0
9
9
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
9
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
17
0
0
9
0
0
0
% F
% Gly:
9
0
0
9
9
25
0
0
42
9
0
0
17
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
17
% I
% Lys:
0
17
0
9
0
0
0
0
0
0
0
59
0
0
0
% K
% Leu:
9
9
0
9
59
9
17
0
0
0
9
9
9
17
0
% L
% Met:
0
9
0
9
0
17
17
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
9
0
0
9
0
0
% N
% Pro:
42
9
50
0
0
9
9
17
9
9
0
0
0
9
9
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
9
9
0
0
0
17
9
% R
% Ser:
17
9
0
0
0
0
0
0
9
9
59
0
0
0
0
% S
% Thr:
9
0
9
0
0
0
0
9
9
42
0
0
0
0
9
% T
% Val:
0
9
9
0
9
17
0
0
0
0
0
9
0
0
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
0
0
0
0
0
59
9
0
9
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _