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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLK1 All Species: 20
Human Site: T373 Identified Species: 44
UniProt: P80370 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P80370 NP_003827.3 383 41300 T373 P E K I D M T T F S K E A G D
Chimpanzee Pan troglodytes XP_518495 383 40470 L373 G L P L P P D L P P E P G K T
Rhesus Macaque Macaca mulatta XP_001106331 383 41270 T373 P E K I D M T T F S K E A G G
Dog Lupus familis XP_547982 526 56645 T516 P E K I D M T T F S K E A G E
Cat Felis silvestris
Mouse Mus musculus Q09163 385 41302 T375 P E K I D M T T F N K E A G D
Rat Rattus norvegicus P97677 714 77360 S685 P D R K R P E S V Y S T S K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513159 426 45458 T417 F P E K V K L T S Y S T C S A
Chicken Gallus gallus NP_001135726 386 41345 T377 F P E K I K L T N Y T K N Y T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q9IAT6 664 72529 S591 N K D M A L R S T S V D T H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10041 833 88822 V779 A E G K R I S V L G E G S Y C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P49013 570 61097 T558 K V G Q D K W T R Y E Q S F A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.9 96.3 63.3 N.A. 84.9 23.3 N.A. 43.6 52.8 N.A. 24.2 N.A. 20.7 N.A. N.A. 23.1
Protein Similarity: 100 48 97.1 67.4 N.A. 89.6 32.2 N.A. 56.3 66 N.A. 34.3 N.A. 30.4 N.A. N.A. 35.2
P-Site Identity: 100 0 93.3 93.3 N.A. 93.3 13.3 N.A. 6.6 6.6 N.A. 6.6 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 13.3 93.3 100 N.A. 100 40 N.A. 13.3 20 N.A. 40 N.A. 33.3 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 0 0 0 0 0 0 0 37 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % C
% Asp: 0 10 10 0 46 0 10 0 0 0 0 10 0 0 28 % D
% Glu: 0 46 19 0 0 0 10 0 0 0 28 37 0 0 10 % E
% Phe: 19 0 0 0 0 0 0 0 37 0 0 0 0 10 0 % F
% Gly: 10 0 19 0 0 0 0 0 0 10 0 10 10 37 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 37 10 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 10 37 37 0 28 0 0 0 0 37 10 0 19 0 % K
% Leu: 0 10 0 10 0 10 19 10 10 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 37 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 10 10 0 0 10 0 0 % N
% Pro: 46 19 10 0 10 19 0 0 10 10 0 10 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 10 0 19 0 10 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 10 19 10 37 19 0 28 10 10 % S
% Thr: 0 0 0 0 0 0 37 64 10 0 10 19 10 0 19 % T
% Val: 0 10 0 0 10 0 0 10 10 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 37 0 0 0 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _