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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLK1
All Species:
20
Human Site:
T373
Identified Species:
44
UniProt:
P80370
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P80370
NP_003827.3
383
41300
T373
P
E
K
I
D
M
T
T
F
S
K
E
A
G
D
Chimpanzee
Pan troglodytes
XP_518495
383
40470
L373
G
L
P
L
P
P
D
L
P
P
E
P
G
K
T
Rhesus Macaque
Macaca mulatta
XP_001106331
383
41270
T373
P
E
K
I
D
M
T
T
F
S
K
E
A
G
G
Dog
Lupus familis
XP_547982
526
56645
T516
P
E
K
I
D
M
T
T
F
S
K
E
A
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q09163
385
41302
T375
P
E
K
I
D
M
T
T
F
N
K
E
A
G
D
Rat
Rattus norvegicus
P97677
714
77360
S685
P
D
R
K
R
P
E
S
V
Y
S
T
S
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513159
426
45458
T417
F
P
E
K
V
K
L
T
S
Y
S
T
C
S
A
Chicken
Gallus gallus
NP_001135726
386
41345
T377
F
P
E
K
I
K
L
T
N
Y
T
K
N
Y
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9IAT6
664
72529
S591
N
K
D
M
A
L
R
S
T
S
V
D
T
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10041
833
88822
V779
A
E
G
K
R
I
S
V
L
G
E
G
S
Y
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P49013
570
61097
T558
K
V
G
Q
D
K
W
T
R
Y
E
Q
S
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.9
96.3
63.3
N.A.
84.9
23.3
N.A.
43.6
52.8
N.A.
24.2
N.A.
20.7
N.A.
N.A.
23.1
Protein Similarity:
100
48
97.1
67.4
N.A.
89.6
32.2
N.A.
56.3
66
N.A.
34.3
N.A.
30.4
N.A.
N.A.
35.2
P-Site Identity:
100
0
93.3
93.3
N.A.
93.3
13.3
N.A.
6.6
6.6
N.A.
6.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
93.3
100
N.A.
100
40
N.A.
13.3
20
N.A.
40
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
0
37
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
0
10
10
0
46
0
10
0
0
0
0
10
0
0
28
% D
% Glu:
0
46
19
0
0
0
10
0
0
0
28
37
0
0
10
% E
% Phe:
19
0
0
0
0
0
0
0
37
0
0
0
0
10
0
% F
% Gly:
10
0
19
0
0
0
0
0
0
10
0
10
10
37
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
37
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
37
37
0
28
0
0
0
0
37
10
0
19
0
% K
% Leu:
0
10
0
10
0
10
19
10
10
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
37
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
10
10
0
0
10
0
0
% N
% Pro:
46
19
10
0
10
19
0
0
10
10
0
10
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
0
19
0
10
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
19
10
37
19
0
28
10
10
% S
% Thr:
0
0
0
0
0
0
37
64
10
0
10
19
10
0
19
% T
% Val:
0
10
0
0
10
0
0
10
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
37
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _