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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLK1 All Species: 21.21
Human Site: Y353 Identified Species: 46.67
UniProt: P80370 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P80370 NP_003827.3 383 41300 Y353 K K N L L L Q Y N S G E D L A
Chimpanzee Pan troglodytes XP_518495 383 40470 D355 H Y A P A C Q D Q E C Q V S M
Rhesus Macaque Macaca mulatta XP_001106331 383 41270 Y353 K K N L L L Q Y N S G E D L A
Dog Lupus familis XP_547982 526 56645 Y496 K K N L L L H Y N S G E D L A
Cat Felis silvestris
Mouse Mus musculus Q09163 385 41302 Y355 K K N L L L Q Y N S G E E L A
Rat Rattus norvegicus P97677 714 77360 Y633 A R Y P T V D Y N L I R D L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513159 426 45458 N399 K R R L M T S N N G E T L S V
Chicken Gallus gallus NP_001135726 386 41345 S358 K K N F L L K S S N G E N L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q9IAT6 664 72529 S561 V N N R I S L S P T S P L G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10041 833 88822 K683 G G N P N I I K N T W D K S V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P49013 570 61097 T533 G Q E V L Y T T W I E S S M V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.9 96.3 63.3 N.A. 84.9 23.3 N.A. 43.6 52.8 N.A. 24.2 N.A. 20.7 N.A. N.A. 23.1
Protein Similarity: 100 48 97.1 67.4 N.A. 89.6 32.2 N.A. 56.3 66 N.A. 34.3 N.A. 30.4 N.A. N.A. 35.2
P-Site Identity: 100 6.6 100 93.3 N.A. 93.3 26.6 N.A. 20 53.3 N.A. 6.6 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 93.3 N.A. 100 40 N.A. 33.3 86.6 N.A. 20 N.A. 33.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 10 0 0 0 0 0 0 0 0 0 37 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 10 0 0 0 10 37 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 10 19 46 10 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 19 10 0 0 0 0 0 0 0 10 46 0 0 10 0 % G
% His: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 10 0 0 10 10 0 0 0 0 % I
% Lys: 55 46 0 0 0 0 10 10 0 0 0 0 10 0 10 % K
% Leu: 0 0 0 46 55 46 10 0 0 10 0 0 19 55 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 10 % M
% Asn: 0 10 64 0 10 0 0 10 64 10 0 0 10 0 0 % N
% Pro: 0 0 0 28 0 0 0 0 10 0 0 10 0 0 0 % P
% Gln: 0 10 0 0 0 0 37 0 10 0 0 10 0 0 0 % Q
% Arg: 0 19 10 10 0 0 0 0 0 0 0 10 0 0 10 % R
% Ser: 0 0 0 0 0 10 10 19 10 37 10 10 10 28 10 % S
% Thr: 0 0 0 0 10 10 10 10 0 19 0 10 0 0 0 % T
% Val: 10 0 0 10 0 10 0 0 0 0 0 0 10 0 28 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % W
% Tyr: 0 10 10 0 0 10 0 46 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _