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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIM1
All Species:
17.88
Human Site:
S373
Identified Species:
35.76
UniProt:
P81133
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P81133
NP_005059.2
766
85515
S373
D
N
R
K
G
A
K
S
R
L
S
S
S
K
S
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
S373
D
N
R
K
G
A
K
S
R
L
S
S
S
K
S
Rhesus Macaque
Macaca mulatta
XP_001086054
766
85453
S373
D
N
R
K
G
A
K
S
R
L
S
S
S
K
S
Dog
Lupus familis
XP_539058
766
85506
S373
D
N
R
K
G
A
K
S
R
L
S
S
S
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61045
765
85522
K372
S
D
N
R
K
G
A
K
S
R
L
S
S
S
K
Rat
Rattus norvegicus
O35800
825
92301
T383
T
K
V
E
S
E
D
T
S
C
L
F
D
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506044
764
85619
A372
D
S
R
K
G
S
K
A
R
L
S
S
T
K
S
Chicken
Gallus gallus
Q9YIB9
811
90524
T383
S
K
D
D
W
D
D
T
N
S
L
F
E
K
L
Frog
Xenopus laevis
Q9I8A9
805
90946
N384
T
E
L
N
E
E
N
N
S
E
C
L
F
D
K
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
Y356
S
T
K
P
S
F
T
Y
N
S
P
S
N
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05709
697
76457
L308
T
G
Y
E
P
Q
D
L
I
E
K
T
L
Y
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782984
820
91461
S372
K
S
K
K
K
S
K
S
S
K
Y
Q
P
Y
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99
98.6
N.A.
96.6
25.2
N.A.
91.3
25.5
20.3
72.3
N.A.
41.9
N.A.
N.A.
42.6
Protein Similarity:
100
99.7
99.2
99.4
N.A.
98.4
41.9
N.A.
96
43.1
38.6
81.5
N.A.
54.3
N.A.
N.A.
55.9
P-Site Identity:
100
100
100
100
N.A.
13.3
6.6
N.A.
73.3
6.6
0
6.6
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
26.6
20
N.A.
100
13.3
6.6
20
N.A.
13.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
34
9
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% C
% Asp:
42
9
9
9
0
9
25
0
0
0
0
0
9
9
0
% D
% Glu:
0
9
0
17
9
17
0
0
0
17
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
17
9
0
0
% F
% Gly:
0
9
0
0
42
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
9
17
17
50
17
0
50
9
0
9
9
0
0
59
17
% K
% Leu:
0
0
9
0
0
0
0
9
0
42
25
9
9
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
34
9
9
0
0
9
9
17
0
0
0
9
0
0
% N
% Pro:
0
0
0
9
9
0
0
0
0
0
9
0
9
9
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
17
% Q
% Arg:
0
0
42
9
0
0
0
0
42
9
0
0
0
0
0
% R
% Ser:
25
17
0
0
17
17
0
42
34
17
42
59
42
9
42
% S
% Thr:
25
9
0
0
0
0
9
17
0
0
0
9
9
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
9
0
0
9
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _