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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIM1
All Species:
24.55
Human Site:
S562
Identified Species:
49.09
UniProt:
P81133
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P81133
NP_005059.2
766
85515
S562
Q
S
S
P
H
E
P
S
K
I
E
T
L
I
R
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
S562
Q
S
S
P
H
E
P
S
K
I
E
T
L
I
R
Rhesus Macaque
Macaca mulatta
XP_001086054
766
85453
S562
Q
S
S
P
H
E
P
S
K
I
E
T
L
I
R
Dog
Lupus familis
XP_539058
766
85506
S562
Q
S
S
P
H
E
P
S
K
I
E
T
L
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61045
765
85522
S561
Q
N
S
P
H
E
P
S
K
I
E
T
L
I
R
Rat
Rattus norvegicus
O35800
825
92301
Q572
I
P
M
D
D
D
F
Q
L
R
S
F
D
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506044
764
85619
S561
Q
S
S
P
H
E
P
S
K
I
E
T
L
I
R
Chicken
Gallus gallus
Q9YIB9
811
90524
L572
P
M
D
D
D
F
Q
L
R
S
F
D
Q
L
S
Frog
Xenopus laevis
Q9I8A9
805
90946
F573
D
D
F
Q
L
R
T
F
D
Q
L
S
S
L
E
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
S545
D
G
G
S
A
S
D
S
G
D
R
F
R
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05709
697
76457
P497
E
P
E
L
P
L
Q
P
A
V
T
P
V
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782984
820
91461
T561
E
T
L
S
Q
S
C
T
S
M
T
S
P
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99
98.6
N.A.
96.6
25.2
N.A.
91.3
25.5
20.3
72.3
N.A.
41.9
N.A.
N.A.
42.6
Protein Similarity:
100
99.7
99.2
99.4
N.A.
98.4
41.9
N.A.
96
43.1
38.6
81.5
N.A.
54.3
N.A.
N.A.
55.9
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
100
0
0
6.6
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
100
13.3
13.3
6.6
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
9
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
9
17
17
9
9
0
9
9
0
9
9
0
9
% D
% Glu:
17
0
9
0
0
50
0
0
0
0
50
0
0
0
9
% E
% Phe:
0
0
9
0
0
9
9
9
0
0
9
17
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
9
0
0
0
0
0
0
0
0
50
0
0
0
50
0
% I
% Lys:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
9
9
0
9
9
0
9
0
50
17
9
% L
% Met:
0
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
9
17
0
50
9
0
50
9
0
0
0
9
9
9
9
% P
% Gln:
50
0
0
9
9
0
17
9
0
9
0
0
9
9
0
% Q
% Arg:
0
0
0
0
0
9
0
0
9
9
9
0
9
0
50
% R
% Ser:
0
42
50
17
0
17
0
59
9
9
9
17
9
0
9
% S
% Thr:
0
9
0
0
0
0
9
9
0
0
17
50
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _