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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIM1
All Species:
23.03
Human Site:
S651
Identified Species:
46.06
UniProt:
P81133
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P81133
NP_005059.2
766
85515
S651
H
E
N
D
Y
D
N
S
P
T
A
L
S
R
I
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
S651
R
E
N
D
Y
D
N
S
P
T
A
L
S
R
I
Rhesus Macaque
Macaca mulatta
XP_001086054
766
85453
S651
H
E
N
D
Y
D
N
S
P
T
T
L
S
R
I
Dog
Lupus familis
XP_539058
766
85506
S651
H
E
N
D
Y
D
N
S
P
T
A
L
S
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61045
765
85522
S650
H
E
N
D
Y
D
N
S
P
T
A
L
S
R
I
Rat
Rattus norvegicus
O35800
825
92301
S664
S
A
Y
S
G
T
H
S
R
T
A
S
P
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506044
764
85619
S650
Q
E
N
D
Y
E
N
S
P
T
A
L
S
R
L
Chicken
Gallus gallus
Q9YIB9
811
90524
E663
R
A
G
K
G
T
L
E
Q
T
E
K
S
C
P
Frog
Xenopus laevis
Q9I8A9
805
90946
L680
L
N
K
R
C
T
I
L
D
E
E
L
N
P
K
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
P631
V
I
S
P
A
P
S
P
V
P
L
S
R
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05709
697
76457
E583
S
S
G
V
Y
S
T
E
M
Q
Y
P
D
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782984
820
91461
N685
N
S
S
S
A
T
D
N
R
D
S
R
D
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99
98.6
N.A.
96.6
25.2
N.A.
91.3
25.5
20.3
72.3
N.A.
41.9
N.A.
N.A.
42.6
Protein Similarity:
100
99.7
99.2
99.4
N.A.
98.4
41.9
N.A.
96
43.1
38.6
81.5
N.A.
54.3
N.A.
N.A.
55.9
P-Site Identity:
100
93.3
93.3
100
N.A.
100
20
N.A.
80
13.3
6.6
0
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
26.6
N.A.
93.3
13.3
13.3
13.3
N.A.
6.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
17
0
0
0
0
0
50
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
50
0
42
9
0
9
9
0
0
17
9
0
% D
% Glu:
0
50
0
0
0
9
0
17
0
9
17
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
17
0
0
0
0
0
0
0
0
0
0
% G
% His:
34
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% H
% Ile:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
42
% I
% Lys:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
9
% K
% Leu:
9
0
0
0
0
0
9
9
0
0
9
59
0
17
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
9
9
50
0
0
0
50
9
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
9
0
9
0
9
50
9
0
9
9
9
9
% P
% Gln:
9
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% Q
% Arg:
17
0
0
9
0
0
0
0
17
0
0
9
9
50
9
% R
% Ser:
17
17
17
17
0
9
9
59
0
0
9
17
59
0
9
% S
% Thr:
0
0
0
0
0
34
9
0
0
67
9
0
0
9
9
% T
% Val:
9
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
59
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _