KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIM1
All Species:
17.88
Human Site:
Y294
Identified Species:
35.76
UniProt:
P81133
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P81133
NP_005059.2
766
85515
Y294
K
G
Q
V
T
T
K
Y
Y
R
F
L
A
K
H
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
Y294
K
G
Q
V
T
T
K
Y
Y
R
F
L
A
K
H
Rhesus Macaque
Macaca mulatta
XP_001086054
766
85453
Y294
K
G
Q
V
T
T
K
Y
Y
R
F
L
A
K
H
Dog
Lupus familis
XP_539058
766
85506
Y294
K
G
Q
V
T
T
K
Y
Y
R
F
L
A
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q61045
765
85522
K293
V
K
G
Q
V
T
T
K
Y
Y
R
F
L
A
K
Rat
Rattus norvegicus
O35800
825
92301
Q304
K
G
Q
V
T
T
G
Q
Y
R
M
L
A
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506044
764
85619
K293
V
K
G
Q
V
T
T
K
Y
Y
R
F
L
A
K
Chicken
Gallus gallus
Q9YIB9
811
90524
Q304
K
G
Q
V
T
T
G
Q
Y
R
M
L
A
K
Q
Frog
Xenopus laevis
Q9I8A9
805
90946
Q305
K
G
Q
V
T
T
G
Q
Y
R
M
L
A
K
K
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
L277
H
S
C
D
T
F
H
L
R
C
A
H
H
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05709
697
76457
K229
G
L
T
T
S
G
F
K
V
I
H
C
S
G
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782984
820
91461
Y293
K
G
Q
A
T
T
R
Y
F
R
F
L
S
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99
98.6
N.A.
96.6
25.2
N.A.
91.3
25.5
20.3
72.3
N.A.
41.9
N.A.
N.A.
42.6
Protein Similarity:
100
99.7
99.2
99.4
N.A.
98.4
41.9
N.A.
96
43.1
38.6
81.5
N.A.
54.3
N.A.
N.A.
55.9
P-Site Identity:
100
100
100
100
N.A.
13.3
73.3
N.A.
13.3
73.3
73.3
6.6
N.A.
0
N.A.
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
73.3
N.A.
13.3
73.3
73.3
6.6
N.A.
20
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
9
0
59
17
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
9
0
9
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
9
0
9
0
42
17
0
0
0
% F
% Gly:
9
67
17
0
0
9
25
0
0
0
0
0
0
9
0
% G
% His:
9
0
0
0
0
0
9
0
0
0
9
9
9
0
42
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
67
17
0
0
0
0
34
25
0
0
0
0
0
67
25
% K
% Leu:
0
9
0
0
0
0
0
9
0
0
0
67
17
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
67
17
0
0
0
25
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
9
0
9
67
17
0
0
0
9
% R
% Ser:
0
9
0
0
9
0
0
0
0
0
0
0
17
0
0
% S
% Thr:
0
0
9
9
75
84
17
0
0
0
0
0
0
0
0
% T
% Val:
17
0
0
59
17
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
75
17
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _