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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM189B All Species: 14.85
Human Site: S70 Identified Species: 46.67
UniProt: P81408 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P81408 NP_006580 668 71355 S70 S I K R S C P S W A G F S L A
Chimpanzee Pan troglodytes XP_001155325 668 71317 S70 S I K R S C P S W A G F S L A
Rhesus Macaque Macaca mulatta XP_001112812 516 55091
Dog Lupus familis XP_547550 671 71600 S70 S I K R S C P S W A G F S L A
Cat Felis silvestris
Mouse Mus musculus Q5HZJ5 669 71997 S70 S I K R S C P S W A G F S L A
Rat Rattus norvegicus Q62645 1323 143083 S570 A R S N G T V S P S A F L E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516227 448 49517
Chicken Gallus gallus XP_413772 724 79324 L72 E A Q V E E V L L S G L I G V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 77 95 N.A. 94 20.1 N.A. 21.5 29.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 77.2 96.7 N.A. 96.1 28.7 N.A. 33.2 44.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 100 13.3 N.A. 0 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 0 100 N.A. 100 26.6 N.A. 0 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 0 0 0 0 0 0 0 50 13 0 0 0 50 % A
% Cys: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 13 0 0 0 13 13 0 0 0 0 0 0 0 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 63 0 0 0 % F
% Gly: 0 0 0 0 13 0 0 0 0 0 63 0 0 13 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 50 0 0 0 0 0 0 0 0 0 0 13 0 0 % I
% Lys: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 13 13 0 0 13 13 50 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 50 0 13 0 0 0 0 0 13 % P
% Gln: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 13 0 50 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 50 0 13 0 50 0 0 63 0 25 0 0 50 0 0 % S
% Thr: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 13 0 0 25 0 0 0 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _