KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM189B
All Species:
13.64
Human Site:
Y251
Identified Species:
42.86
UniProt:
P81408
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P81408
NP_006580
668
71355
Y251
P
V
P
P
P
P
Y
Y
P
P
E
Y
T
C
S
Chimpanzee
Pan troglodytes
XP_001155325
668
71317
Y251
P
V
P
P
P
P
Y
Y
P
P
E
Y
T
C
S
Rhesus Macaque
Macaca mulatta
XP_001112812
516
55091
A120
S
V
L
S
C
K
N
A
Q
L
A
R
D
F
Q
Dog
Lupus familis
XP_547550
671
71600
Y251
P
V
P
P
P
P
Y
Y
P
P
E
Y
T
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5HZJ5
669
71997
Y252
P
V
P
P
P
P
Y
Y
P
P
E
Y
T
C
S
Rat
Rattus norvegicus
Q62645
1323
143083
E768
N
Y
M
A
R
K
D
E
G
C
K
L
V
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516227
448
49517
E51
K
I
C
F
C
C
E
E
F
Q
P
A
K
C
T
Chicken
Gallus gallus
XP_413772
724
79324
R261
P
V
V
E
A
Q
S
R
S
L
H
L
E
F
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
77
95
N.A.
94
20.1
N.A.
21.5
29.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
77.2
96.7
N.A.
96.1
28.7
N.A.
33.2
44.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
0
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
6.6
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
13
0
0
13
0
0
13
13
0
0
0
% A
% Cys:
0
0
13
0
25
13
0
0
0
13
0
0
0
63
0
% C
% Asp:
0
0
0
0
0
0
13
0
0
0
0
0
13
0
0
% D
% Glu:
0
0
0
13
0
0
13
25
0
0
50
0
13
0
0
% E
% Phe:
0
0
0
13
0
0
0
0
13
0
0
0
0
25
0
% F
% Gly:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
13
0
0
0
0
25
0
0
0
0
13
0
13
0
0
% K
% Leu:
0
0
13
0
0
0
0
0
0
25
0
25
0
0
0
% L
% Met:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
63
0
50
50
50
50
0
0
50
50
13
0
0
0
13
% P
% Gln:
0
0
0
0
0
13
0
0
13
13
0
0
0
0
13
% Q
% Arg:
0
0
0
0
13
0
0
13
0
0
0
13
0
0
0
% R
% Ser:
13
0
0
13
0
0
13
0
13
0
0
0
0
0
50
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
50
13
13
% T
% Val:
0
75
13
0
0
0
0
0
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
0
0
0
0
50
50
0
0
0
50
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _