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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 17.88
Human Site: S131 Identified Species: 24.58
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 S131 R P E E E V K S S L H E S L H
Chimpanzee Pan troglodytes XP_526227 1093 122795 S131 R P E E E V K S S L R E S L H
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 S131 R P E E E V K S S L H E S L H
Dog Lupus familis XP_533766 1089 122761 S131 R P E E E V K S T L Q E S L H
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 S131 R P E E E V K S S L Q E S S S
Rat Rattus norvegicus NP_446123 1093 121882 S131 P E E E V K S S L Q E P S S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 H131 E E V K S N L H E S P H S V Q
Chicken Gallus gallus O42184 1433 161009 A135 K V L T E D E A N G T Q T A H
Frog Xenopus laevis Q5PQ23 649 75475
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 K131 R E K E D K D K E L V D N D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 V83 I P P T P T S V P G S A A Y G
Honey Bee Apis mellifera XP_394037 1326 150590 V158 K N I H D Q N V L S Q D V N T
Nematode Worm Caenorhab. elegans P02566 1966 225108 R713 N G V L E G I R I C R K G F P
Sea Urchin Strong. purpuratus XP_785821 1176 131318 A131 G K K L Q T P A K S E D V A K
Poplar Tree Populus trichocarpa XP_002303293 975 109171 V126 I A E K K D D V I S D T G K A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 K107 E E E A G S V K L A T E Q A V
Baker's Yeast Sacchar. cerevisiae P47166 707 81153
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 93.3 100 86.6 N.A. 80 26.6 N.A. 6.6 13.3 0 20 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 93.3 100 93.3 N.A. 80 26.6 N.A. 20 53.3 0 46.6 N.A. 13.3 20 13.3 26.6
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 0 N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 6 0 0 0 12 0 6 0 6 6 18 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 12 12 0 0 0 6 18 0 6 0 % D
% Glu: 12 24 48 42 42 0 6 0 12 0 12 36 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % F
% Gly: 6 6 0 0 6 6 0 0 0 12 0 0 12 0 6 % G
% His: 0 0 0 6 0 0 0 6 0 0 12 6 0 0 30 % H
% Ile: 12 0 6 0 0 0 6 0 12 0 0 0 0 0 0 % I
% Lys: 12 6 12 12 6 12 30 12 6 0 0 6 0 6 6 % K
% Leu: 0 0 6 12 0 0 6 0 18 36 0 0 0 24 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 6 0 0 0 6 6 0 6 0 0 0 6 6 0 % N
% Pro: 6 36 6 0 6 0 6 0 6 0 6 6 0 0 12 % P
% Gln: 0 0 0 0 6 6 0 0 0 6 18 6 6 0 6 % Q
% Arg: 36 0 0 0 0 0 0 6 0 0 12 0 0 0 0 % R
% Ser: 0 0 0 0 6 6 12 36 24 24 6 0 42 12 12 % S
% Thr: 0 0 0 12 0 12 0 0 6 0 12 6 6 0 6 % T
% Val: 0 6 12 0 6 30 6 18 0 0 6 0 12 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _