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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 20
Human Site: S285 Identified Species: 27.5
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 S285 E T T D S K S S L H L M Q T S
Chimpanzee Pan troglodytes XP_526227 1093 122795 S285 E T T D S K S S L H L M Q T S
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 S284 E T T D S K S S L H L M Q T S
Dog Lupus familis XP_533766 1089 122761 H283 T D S K S S L H L M Q T S F Q
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 H283 S D A K S S L H L M Q T S F Q
Rat Rattus norvegicus NP_446123 1093 121882 H284 S D A K S S L H L M Q T S F Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 S291 E A A D S K S S L H L M Q T S
Chicken Gallus gallus O42184 1433 161009 T383 R A E V A K A T S H V G E I E
Frog Xenopus laevis Q5PQ23 649 75475
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 G311 E T A E A K A G L H L M Q G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 K235 G K S P A P A K T G T V D Q S
Honey Bee Apis mellifera XP_394037 1326 150590 S324 G D W K S D T S P Y L S P I D
Nematode Worm Caenorhab. elegans P02566 1966 225108 R916 Q L S D A E E R L A K L E A Q
Sea Urchin Strong. purpuratus XP_785821 1176 131318 L290 D Q P L G Q S L E S S N S T S
Poplar Tree Populus trichocarpa XP_002303293 975 109171 S278 S S S S Q P V S A E V S E M V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 S259 S S K N F E V S P D I N H V N
Baker's Yeast Sacchar. cerevisiae P47166 707 81153 R10 K K L S L E E R L S L A T K K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 100 13.3 N.A. 13.3 13.3 N.A. 86.6 13.3 0 60 N.A. 6.6 20 13.3 20
P-Site Similarity: 100 100 100 20 N.A. 13.3 13.3 N.A. 86.6 46.6 0 80 N.A. 33.3 33.3 53.3 33.3
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 33.3 N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 24 0 24 0 18 0 6 6 0 6 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 24 0 30 0 6 0 0 0 6 0 0 6 0 6 % D
% Glu: 30 0 6 6 0 18 12 0 6 6 0 0 18 0 6 % E
% Phe: 0 0 0 0 6 0 0 0 0 0 0 0 0 18 0 % F
% Gly: 12 0 0 0 6 0 0 6 0 6 0 6 0 6 0 % G
% His: 0 0 0 0 0 0 0 18 0 36 0 0 6 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 6 0 0 12 0 % I
% Lys: 6 12 6 24 0 36 0 6 0 0 6 0 0 6 6 % K
% Leu: 0 6 6 6 6 0 18 6 59 0 42 6 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 18 0 30 0 6 0 % M
% Asn: 0 0 0 6 0 0 0 0 0 0 0 12 0 0 6 % N
% Pro: 0 0 6 6 0 12 0 0 12 0 0 0 6 0 0 % P
% Gln: 6 6 0 0 6 6 0 0 0 0 18 0 30 6 24 % Q
% Arg: 6 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % R
% Ser: 24 12 24 12 48 18 30 42 6 12 6 12 24 0 42 % S
% Thr: 6 24 18 0 0 0 6 6 6 0 6 18 6 30 0 % T
% Val: 0 0 0 6 0 0 12 0 0 0 12 6 0 6 6 % V
% Trp: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _