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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
21.21
Human Site:
S297
Identified Species:
29.17
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S297
Q
T
S
F
Q
L
L
S
A
S
A
C
P
E
Y
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S297
Q
T
S
F
Q
L
L
S
A
S
A
C
P
E
Y
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
S296
Q
T
S
F
Q
L
L
S
A
S
A
C
P
E
Y
Dog
Lupus familis
XP_533766
1089
122761
S295
S
F
Q
L
L
S
A
S
A
C
P
E
Y
N
R
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
S295
S
F
Q
L
L
S
A
S
A
C
P
E
Y
S
R
Rat
Rattus norvegicus
NP_446123
1093
121882
S296
S
F
Q
L
L
S
A
S
A
C
P
E
Y
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
S303
Q
T
S
F
Q
L
L
S
A
S
A
C
P
E
Y
Chicken
Gallus gallus
O42184
1433
161009
L395
E
I
E
Q
E
L
A
L
V
R
D
G
H
D
R
Frog
Xenopus laevis
Q5PQ23
649
75475
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
S323
Q
G
S
F
Q
L
L
S
A
S
T
C
S
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
S247
D
Q
S
Y
S
S
T
S
S
D
I
E
I
I
S
Honey Bee
Apis mellifera
XP_394037
1326
150590
D336
P
I
D
Q
K
N
S
D
S
S
S
I
L
D
R
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
S928
E
A
Q
Q
K
D
A
S
K
Q
L
S
E
L
N
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
E302
S
T
S
T
G
T
V
E
A
D
E
K
E
G
E
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
L290
E
M
V
H
E
F
S
L
S
D
A
S
P
L
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
P271
H
V
N
R
I
E
S
P
V
A
H
P
S
L
I
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
N22
T
K
K
G
R
K
K
N
K
R
S
T
S
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
100
6.6
0
66.6
N.A.
13.3
6.6
6.6
20
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
100
26.6
0
80
N.A.
26.6
33.3
20
26.6
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
0
30
0
53
6
30
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
18
0
30
0
0
0
% C
% Asp:
6
0
6
0
0
6
0
6
0
18
6
0
0
18
6
% D
% Glu:
18
0
6
0
12
6
0
6
0
0
6
24
12
24
6
% E
% Phe:
0
18
0
30
0
6
0
0
0
0
0
0
0
0
6
% F
% Gly:
0
6
0
6
6
0
0
0
0
0
0
6
0
12
0
% G
% His:
6
0
0
6
0
0
0
0
0
0
6
0
6
0
0
% H
% Ile:
0
12
0
0
6
0
0
0
0
0
6
6
6
6
6
% I
% Lys:
0
6
6
0
12
6
6
0
12
0
0
6
0
0
0
% K
% Leu:
0
0
0
18
18
36
30
12
0
0
6
0
6
18
6
% L
% Met:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
0
0
6
0
6
0
0
0
0
0
12
6
% N
% Pro:
6
0
0
0
0
0
0
6
0
0
18
6
30
0
0
% P
% Gln:
30
6
24
18
30
0
0
0
0
6
0
0
0
0
0
% Q
% Arg:
0
0
0
6
6
0
0
0
0
12
0
0
0
0
30
% R
% Ser:
24
0
42
0
6
24
18
59
18
36
12
12
18
6
6
% S
% Thr:
6
30
0
6
0
6
6
0
0
0
6
6
0
0
0
% T
% Val:
0
6
6
0
0
0
6
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
0
0
0
0
0
18
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _