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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
13.64
Human Site:
S377
Identified Species:
18.75
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S377
V
E
S
A
E
G
K
S
E
E
V
N
E
T
L
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S377
V
E
S
A
E
G
K
S
E
E
V
N
E
T
L
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
S376
V
E
S
A
E
G
K
S
E
E
V
N
E
T
L
Dog
Lupus familis
XP_533766
1089
122761
E375
S
V
E
G
K
S
E
E
V
V
N
E
T
L
I
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
E375
S
T
E
E
N
A
E
E
E
E
G
N
E
T
L
Rat
Rattus norvegicus
NP_446123
1093
121882
E376
S
T
E
E
N
V
E
E
E
E
G
N
E
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
S383
A
E
S
M
G
R
K
S
E
A
E
V
S
E
T
Chicken
Gallus gallus
O42184
1433
161009
L475
K
E
L
E
Q
S
L
L
F
E
K
T
K
A
D
Frog
Xenopus laevis
Q5PQ23
649
75475
G44
G
A
K
L
K
K
K
G
M
G
N
L
R
R
S
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
E403
V
P
Q
T
K
Q
E
E
E
E
G
M
I
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
R327
V
I
E
A
R
E
Q
R
L
L
Q
S
E
R
Q
Honey Bee
Apis mellifera
XP_394037
1326
150590
S416
L
H
L
H
K
S
L
S
S
G
H
S
M
K
V
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
K1008
I
A
K
L
N
K
E
K
K
H
Q
E
E
I
N
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
S382
S
S
S
N
G
K
R
S
P
T
D
S
D
F
S
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
A370
E
T
A
L
Q
G
A
A
R
Q
A
Q
A
K
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
M351
K
T
K
K
E
I
K
M
L
E
N
A
L
Q
G
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
F102
D
H
N
R
T
D
C
F
D
D
T
M
V
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
0
N.A.
40
40
N.A.
33.3
13.3
6.6
20
N.A.
20
6.6
6.6
13.3
P-Site Similarity:
100
100
100
20
N.A.
46.6
46.6
N.A.
33.3
26.6
13.3
33.3
N.A.
33.3
33.3
26.6
33.3
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
12
6
24
0
6
6
6
0
6
6
6
6
6
6
% A
% Cys:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
6
0
0
6
6
6
0
6
0
6
% D
% Glu:
6
30
24
18
24
6
30
24
42
48
6
12
42
12
0
% E
% Phe:
0
0
0
0
0
0
0
6
6
0
0
0
0
6
0
% F
% Gly:
6
0
0
6
12
24
0
6
0
12
18
0
0
0
6
% G
% His:
0
12
0
6
0
0
0
0
0
6
6
0
0
0
0
% H
% Ile:
6
6
0
0
0
6
0
0
0
0
0
0
6
6
6
% I
% Lys:
12
0
18
6
24
18
36
6
6
0
6
0
6
12
0
% K
% Leu:
6
0
12
18
0
0
12
6
12
6
0
6
6
6
36
% L
% Met:
0
0
0
6
0
0
0
6
6
0
0
12
6
0
0
% M
% Asn:
0
0
6
6
18
0
0
0
0
0
18
30
0
0
6
% N
% Pro:
0
6
0
0
0
0
0
0
6
0
0
0
0
0
0
% P
% Gln:
0
0
6
0
12
6
6
0
0
6
12
6
0
6
6
% Q
% Arg:
0
0
0
6
6
6
6
6
6
0
0
0
6
12
0
% R
% Ser:
24
6
30
0
0
18
0
36
6
0
0
18
6
6
18
% S
% Thr:
0
24
0
6
6
0
0
0
0
6
6
6
6
30
6
% T
% Val:
30
6
0
0
0
6
0
0
6
6
18
6
6
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _