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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 11.21
Human Site: S414 Identified Species: 15.42
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 S414 Q P D I L V S S T P I N E G Q
Chimpanzee Pan troglodytes XP_526227 1093 122795 S414 Q P D I L V S S T P I N E G Q
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 S413 Q P D I L V S S T P I N E G H
Dog Lupus familis XP_533766 1089 122761 T412 P D I L V S A T P I N E G H T
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 P412 Q P D I L A S P T A G S G G H
Rat Rattus norvegicus NP_446123 1093 121882 P413 Q P D T L A S P T P V N V G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 V420 E Q P D V L V V T P P I N E D
Chicken Gallus gallus O42184 1433 161009 R512 L E R D L A L R V K E V A E L
Frog Xenopus laevis Q5PQ23 649 75475 R81 K W E G L T H R L D I T P P D
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 Q440 C E Q V D E L Q E V D Q E P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 A364 N S P D A A D A V Q R L S A L
Honey Bee Apis mellifera XP_394037 1326 150590 S453 S Y T S T S E S T V I T M L E
Nematode Worm Caenorhab. elegans P02566 1966 225108 D1045 K L E Q T L D D L E D S L E R
Sea Urchin Strong. purpuratus XP_785821 1176 131318 A419 V G N I V E Q A S M A L S H R
Poplar Tree Populus trichocarpa XP_002303293 975 109171 E407 K S N D A E I E S L R E E Y H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 K388 K S V T E D L K R K S N E A E
Baker's Yeast Sacchar. cerevisiae P47166 707 81153 Q139 E Y L R L N K Q I D D L T N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 93.3 0 N.A. 53.3 60 N.A. 13.3 6.6 13.3 6.6 N.A. 0 20 0 6.6
P-Site Similarity: 100 100 93.3 26.6 N.A. 60 66.6 N.A. 33.3 6.6 26.6 20 N.A. 6.6 26.6 33.3 40
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 24 6 12 0 6 6 0 6 12 0 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 30 24 6 6 12 6 0 12 18 0 0 0 12 % D
% Glu: 12 12 12 0 6 18 6 6 6 6 6 12 36 18 24 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 6 0 6 0 0 0 0 0 0 6 0 12 30 0 % G
% His: 0 0 0 0 0 0 6 0 0 0 0 0 0 12 18 % H
% Ile: 0 0 6 30 0 0 6 0 6 6 30 6 0 0 0 % I
% Lys: 24 0 0 0 0 0 6 6 0 12 0 0 0 0 0 % K
% Leu: 6 6 6 6 48 12 18 0 12 6 0 18 6 6 12 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 0 6 0 0 % M
% Asn: 6 0 12 0 0 6 0 0 0 0 6 30 6 6 0 % N
% Pro: 6 30 12 0 0 0 0 12 6 30 6 0 6 12 6 % P
% Gln: 30 6 6 6 0 0 6 12 0 6 0 6 0 0 12 % Q
% Arg: 0 0 6 6 0 0 0 12 6 0 12 0 0 0 12 % R
% Ser: 6 18 0 6 0 12 30 24 12 0 6 12 12 0 0 % S
% Thr: 0 0 6 12 12 6 0 6 42 0 0 12 6 0 6 % T
% Val: 6 0 6 6 18 18 6 6 12 12 6 6 6 0 0 % V
% Trp: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 0 0 0 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _