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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 41.52
Human Site: S991 Identified Species: 57.08
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 S991 S I I E N L Q S Q L K L R E G
Chimpanzee Pan troglodytes XP_526227 1093 122795 S991 S I I E N L Q S Q L K L R E G
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 S990 S I I E N L Q S Q L K L R E G
Dog Lupus familis XP_533766 1089 122761 S987 S I I E N L Q S Q L K L R E G
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 S989 S I I E N L Q S Q L K L R E G
Rat Rattus norvegicus NP_446123 1093 121882 S991 S I I E N L Q S Q L K L R E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 S1004 S I I E N L Q S Q L K L K E G
Chicken Gallus gallus O42184 1433 161009 S1262 A S A K T L Q S V V K T L E S
Frog Xenopus laevis Q5PQ23 649 75475 R557 K E Q L Q K S R Q E A N S I S
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 S1034 S V I E S L Q S Q L K L R E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 R840 H L Q W E V S R L Q A E R S V
Honey Bee Apis mellifera XP_394037 1326 150590 E1106 E T D R Y L K E E N I N L K S
Nematode Worm Caenorhab. elegans P02566 1966 225108 R1625 K G K A E L L R I K K K L E G
Sea Urchin Strong. purpuratus XP_785821 1176 131318 S1075 S I I E S L Q S Q L K Q K E G
Poplar Tree Populus trichocarpa XP_002303293 975 109171 S883 S Y M S R L A S M E S I R D S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 L864 L R Q K E G E L A S Y M T R L
Baker's Yeast Sacchar. cerevisiae P47166 707 81153 S615 L E G E L S A S K E L Y D N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 33.3 6.6 86.6 N.A. 6.6 6.6 26.6 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 53.3 6.6 100 N.A. 20 26.6 26.6 93.3
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 26.6 N.A. N.A. 0 13.3 N.A.
P-Site Similarity: 46.6 N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 6 0 0 12 0 6 0 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 6 0 0 0 0 0 0 0 0 0 6 6 0 % D
% Glu: 6 12 0 59 18 0 6 6 6 18 0 6 0 65 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 6 6 0 0 6 0 0 0 0 0 0 0 0 59 % G
% His: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 48 53 0 0 0 0 0 6 0 6 6 0 6 0 % I
% Lys: 12 0 6 12 0 6 6 0 6 6 65 6 12 6 0 % K
% Leu: 12 6 0 6 6 77 6 6 6 53 6 48 18 0 12 % L
% Met: 0 0 6 0 0 0 0 0 6 0 0 6 0 0 0 % M
% Asn: 0 0 0 0 42 0 0 0 0 6 0 12 0 6 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 18 0 6 0 59 0 59 6 0 6 0 0 0 % Q
% Arg: 0 6 0 6 6 0 0 18 0 0 0 0 53 6 0 % R
% Ser: 59 6 0 6 12 6 12 71 0 6 6 0 6 6 24 % S
% Thr: 0 6 0 0 6 0 0 0 0 0 0 6 6 0 0 % T
% Val: 0 6 0 0 0 6 0 0 6 6 0 0 0 0 6 % V
% Trp: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 0 0 6 0 0 0 0 0 6 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _